التفاصيل البيبلوغرافية
| العنوان: |
Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder? |
| المؤلفون: |
Baeza, Inmaculada, de la Serna, Elena, Mezquida, Gisela, Cuesta, Manuel J., Vieta, Eduard, Amoretti, Silvia, Lobo, Antonio, González-Pinto, Ana, Díaz-Caneja, Covadonga M., Corripio, Iluminada, Valli, Isabel, Puig, Olga, Mané, Anna, Bioque, Miquel, Ayora, Miriam, Bernardo, Miquel, Castro-Fornieles, Josefina, García-Rizo, Clemente, González-Díaz, Jairo, de Matteis, Mario, de Diego, Héctor, Grasa, Eva, Roldán, Alejandra, Zorrilla, Iñaki, García-Corres, Edurne, Ruíz-Lázaro, Pedro M, de-la-Cámara, Concepción, Rivero, Olga, Escarti, María José, Casanovas, Francesc, Toll, Alba, Verdolini, Norma, Sagué-Vilabella, Maria, Sugranyes, Gisela, Ilzarbe, Daniel, Contreras, Fernando, González-Blanco, Leticia, García-Portilla, María Paz, Gutierrez, Miguel, Zabala, Arantzazu, Rodríguez-Jiménez, Roberto, Sánchez-Pastor, Luis, Usall, Judith, Butjosa, Anna, Pomarol, Edith, Sarró, Salvador, Ibáñez, Angela, Sánchez-Torres, Ana Maria, Balanzá-Martínez, Vicent |
| المساهمون: |
Instituto de Salud Carlos III, Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya, Universitat de Barcelona |
| المصدر: |
European Child & Adolescent Psychiatry ; ISSN 1018-8827 1435-165X |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Psychiatry and Mental health, Developmental and Educational Psychology, General Medicine, Pediatrics, Perinatology and Child Health |
| الوصف: |
To assess the role of age (early onset psychosis-EOP < 18 years vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on the duration of untreated psychosis (DUP) and prodromal symptoms in a sample of patients with a first episode of psychosis. 331 patients with a first episode of psychosis (7–35 years old) were recruited and 174 (52.6%) diagnosed with SSD or BD at one-year follow-up through a multicenter longitudinal study. The Symptom Onset in Schizophrenia (SOS) inventory, the Positive and Negative Syndrome Scale and the structured clinical interviews for DSM-IV diagnoses were administered. Generalized linear models compared the main effects and group interaction. 273 AOP (25.2 ± 5.1 years; 66.5% male) and 58 EOP patients (15.5 ± 1.8 years; 70.7% male) were included. EOP patients had significantly more prodromal symptoms with a higher frequency of trouble with thinking, avolition and hallucinations than AOP patients, and significantly different median DUP (91 [33–177] vs. 58 [21–140] days; Z = − 2.006, p = 0.045). This was also significantly longer in SSD vs. BD patients (90 [31–155] vs. 30 [7–66] days; Z = − 2.916, p = 0.004) who, moreover had different profiles of prodromal symptoms. When assessing the interaction between age at onset (EOP/AOP) and type of diagnosis (SSD/BD), avolition was significantly higher (Wald statistic = 3.945; p = 0.047), in AOP patients with SSD compared to AOP BD patients (p = 0.004). Awareness of differences in length of DUP and prodromal symptoms in EOP vs. AOP and SSD vs. BD patients could help improve the early detection of psychosis among minors. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s00787-023-02196-7 |
| DOI: |
10.1007/s00787-023-02196-7.pdf |
| DOI: |
10.1007/s00787-023-02196-7/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s00787-023-02196-7Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.19C23794 |
| قاعدة البيانات: |
BASE |
