التفاصيل البيبلوغرافية
| العنوان: |
Prognostic value of insular lobe involvement in temporal lobe epilepsy: A stereoelectroencephalographic study. |
| المؤلفون: |
Blauwblomme, Thomas, David, Olivier, Minotti, Lorella, Job, Anne‐Sophie, Chassagnon, Serge, Hoffman, Dominique, Chabardes, Stéphan, Kahane, Philippe |
| المصدر: |
Epilepsia (Series 4); Sep2013, Vol. 54 Issue 9, p1658-1667, 10p |
| مصطلحات موضوعية: |
TEMPORAL lobe epilepsy, EPILEPSY surgery, STEREOTACTIC radiotherapy, STEREOTACTIC radiosurgery, INTRACEREBRAL transplantation, CEREBRAL cortex |
| مستخلص: |
Purpose Failure of anterior temporal lobectomy for temporal lobe epilepsy has raised the question of insular cortex involvement in these seizures. Because of difficulties in exploring the insula with invasive electroencephalography ( EEG) recordings, only few studies have been performed and this question remains unanswered. Methods Here, we studied 17 patients who underwent surgery for drug-resistant temporal lobe epilepsy, explored with intracerebral electrodes, with at least one electrode coplanar to the insula. We analyzed seizure propagation patterns from temporal lobe structures to the insula, and their effect on outcome. We used an objective measure of the epileptogenicity of the insula for individual cases and group analysis between patients who were seizure-free after surgery and the others. Key Findings All temporal lobe seizures propagated to the insular cortex, with a shorter propagation delay in the case of mesiolateral temporal lobe seizures, thus supporting the existence of a perilimbic network. Epileptogenicity of the insular cortex was not a prognostic factor for outcome after surgery. Significance Insular involvement in temporal lobe seizure is not per se a prognostic factor for surgical outcome. Prognosis may be correlated with larger epileptogenic zones that our stereoelectroencephalography spatial sampling could have underestimated. [ABSTRACT FROM AUTHOR] |
|
Copyright of Epilepsia (Series 4) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder