Texture Analysis of Hippocampal Sclerosis
| العنوان: | Texture Analysis of Hippocampal Sclerosis |
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| المؤلفون: | Li M. Li, Leonardo Bonilha, Eduardo Tinois, Fernando Cendes, Eliane Kobayashi, Giselle Coelho, Gabriela Castellano |
| المصدر: | Epilepsia. 44:1546-1550 |
| بيانات النشر: | Wiley, 2003. |
| سنة النشر: | 2003 |
| مصطلحات موضوعية: | Adult, Male, Pathology, medicine.medical_specialty, Adolescent, Entropy, Hippocampal formation, Hippocampus, Sensitivity and Specificity, Lateralization of brain function, Central nervous system disease, Epilepsy, Atrophy, Image Processing, Computer-Assisted, medicine, Humans, Dominance, Cerebral, Hippocampal sclerosis, Sclerosis, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Temporal Lobe, nervous system diseases, Epilepsy, Temporal Lobe, nervous system, Neurology, Coronal plane, Multivariate Analysis, Female, Neurology (clinical), Psychology, Nuclear medicine, business |
| الوصف: | Summary: Mesial temporal lobe epilepsy (MTLE) is frequently associated with refractory seizures and pathologic features of hippocampal sclerosis (HS). Quantitative magnetic resonance imaging (MRI) techniques can improve the detection and quantification of HS. The objective of this study was to evaluate whether MRI texture analysis can detect hippocampal abnormalities in patients with pathologically proven HS. Methods: Nineteen consecutive patients who underwent surgery for refractory unilateral MTLE and had HS diagnosed on histopathology (12 right and seven left) had their preoperative MRIs evaluated. We performed texture analysis in 3-mm coronal T1-IR MRIs, focusing on the hippocampal head, by using the software MAZDA. Data were compared with those of a group of 78 normal hippocampi from 39 healthy adult volunteers through multivariate analysis of variance and selection of the most significant texture parameters. Results: Overall, almost all parameters of texture could discriminate the group of hippocampi with HS and the group of contralateral hippocampi from the group of normal hippocampi, but the post hoc comparison showed no differences between HS and contralateral hippocampi. Conclusions: These results provide evidence of texture alteration in MRIs of hippocampi with HS and corroborate the hypothesis of bilaterality of hippocampal damage in patients with MTLE, but further studies are needed to investigate the lateralization power of texture analysis. |
| تدمد: | 1528-1167 0013-9580 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbf0564e85b2bc7b84841cc861c80e5Test https://doi.org/10.1111/j.0013-9580.2003.27103.xTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....adbf0564e85b2bc7b84841cc861c80e5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15281167 00139580 |
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