Correlation of echocardiographic findings of pulmonary hypertension with six-minute walk test and plasma pro b-type natriuretic peptide level in systemic lupus erythematous
| العنوان: | Correlation of echocardiographic findings of pulmonary hypertension with six-minute walk test and plasma pro b-type natriuretic peptide level in systemic lupus erythematous |
|---|---|
| المؤلفون: | Saeed Eslami, Farveh Vakilian, Fatemeh Seyyedi khabbaz, Leila Ghofraniha, Zahra Mirfeizi |
| المصدر: | Electronic Physician, Vol 9, Iss 8, Pp 5122-5128 (2017) Electronic Physician |
| بيانات النشر: | Knowledge Kingdom Publishing, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Transthoracic echocardiography, medicine.drug_class, Six-minute walk test, Prevalence, Pulmonary arterial hypertension, Asymptomatic, 03 medical and health sciences, Systemic lupus erythematosus, 0302 clinical medicine, Internal medicine, medicine.artery, Natriuretic peptide, Medicine, 030212 general & internal medicine, 030203 arthritis & rheumatology, lcsh:R5-920, business.industry, medicine.disease, Pulmonary hypertension, Exact test, Pulmonary artery, Cardiology, Mann–Whitney U test, Original Article, medicine.symptom, lcsh:Medicine (General), business, Complication, Serum proBNP levels |
| الوصف: | Introduction: Pulmonary arterial hypertension (PAH) is an increasingly recognized complication of systemic lupus erythematous (SLE), which may remain undiagnosed if asymptomatic. Objective: This study aimed to determine the correlation between echocardiographic findings of PAH and six- minute walk test (6WMT) and serum pro b-type natriuretic peptide (proBNP) level in patients with SLE. Methods: This cross-sectional study was performed on 50 SLE patients selected from patients referring to the outpatient’s department of the Rheumatology Clinic at Imam Reza Hospital in Mashhad, Iran, from July 2013 through September 2014, using resting transthoracic echocardiography to estimate systolic pulmonary artery pressure (sPAP). Variables were summarized as counts and/or percentages or as mean±SD. Inter-group comparisons were made performing two-tailed Fisher’s exact test or Mann–Whitney U test, using SPSS 22. Results: In general, five out of fifty patients were diagnosed to have PAH with sPAP>30 mmHg (range: 31-40 mmHg) based on echocardiographic findings. Spirometric parameters did not show any differences between the two groups (p>0.05), while the difference in total distance walked during six minutes and serum proBNP level between SLE patients with and without PAH was significant (P |
| تدمد: | 2008-5842 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ae4d101f8ee3be87d46646c9cb6afcTest https://doi.org/10.19082/5122Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....50ae4d101f8ee3be87d46646c9cb6afc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20085842 |
|---|