دورية أكاديمية
Renal resistive index in non-alcoholic fatty liver disease as an indicator of early renal affection
| العنوان: | Renal resistive index in non-alcoholic fatty liver disease as an indicator of early renal affection |
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| المؤلفون: | Hossam El-Din A. Mahmoud, Wael A. Yousry, Shereen A. Saleh, Mohamed El Badry, Ahmed Hussein, Mostafa Hassan Ali, Hazem M. El-Hariri |
| المصدر: | Egyptian Liver Journal, Vol 10, Iss 1, Pp 1-8 (2020) |
| بيانات النشر: | SpringerOpen, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Surgery LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | NAFLD, NASH, RRI, CKD, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a possible risk factor for chronic kidney disease (CKD). Renal resistive index (RRI) which is a ratio of peak systolic and end diastolic velocity can test arterial stiffness and endothelial renal dysfunction. The aim of the work is to detect the relation between NAFLD and RRI as an indicator of early renal affection and its relation to the disease severity. This study included 150 subjects divided into 3 groups: patients with NASH, simple steatosis, and control group (50 patients each). All patients were subjected to full history taking, clinical examination, laboratory investigations, abdominal ultrasound examination, and RRI measurement. Results 6.0% of NASH patients had significant fibrosis by NAFLD fibrosis score. RRI was significantly higher in NASH patients with fibrosis (mean = 0.74) than NASH patients without fibrosis (mean = 0.65) and patients with simple steatosis (mean = 0.63). It was the lowest in normal controls (mean = 0.61). There were significant correlations between RRI and age, BMI, serum lipids, liver enzymes, and NAFLD fibrosis score. Multiple linear regression analysis found that age and serum cholesterol were significant independent factors of increased RRI (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-6226 |
| العلاقة: | http://link.springer.com/article/10.1186/s43066-019-0006-7Test; https://doaj.org/toc/2090-6226Test |
| DOI: | 10.1186/s43066-019-0006-7 |
| الوصول الحر: | https://doaj.org/article/e60a5afb52954c5fb77bb211630ef4a7Test |
| رقم الانضمام: | edsdoj.60a5afb52954c5fb77bb211630ef4a7 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20906226 |
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| DOI: | 10.1186/s43066-019-0006-7 |