المؤلفون: Mayumi Nagashimada, Eric Mayoux, Naoto Nagata, Guanliang Chen, Liang Xu, Shuichi Kaneko, Yinhua Ni, Fen Zhuge, Tsuguhito Ota

المصدر: EBioMedicine
EBioMedicine, Vol 20, Iss C, Pp 137-149 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, FGF21, Macrophage, lcsh:Medicine, AST, aspartate aminotransferase, White adipose tissue, 030204 cardiovascular system & hematology, ATMs, adipose tissue macrophages, Brown adipose tissue, EGP, endogenous glucose production, Mice, 0302 clinical medicine, Glucosides, FACS, fluorescence-activated cell sorting, TBARS, thiobarbituric acid reactive substances, Empa, empagliflozin, RER, respiratory exchange ratio, Adiposity, lcsh:R5-920, Glucose tolerance test, medicine.diagnostic_test, NEFA, non-esterified fatty acid, Fatty Acids, CT, computed tomographic, WAT, white adipose tissue, DIO, high-fat-diet-induced obese, General Medicine, TG, triglycerides, Adipose Tissue, H&E, haematoxylin and eosin, GTT, glucose tolerance test, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, NASH, non-alcoholic steatohepatitis, Adipose tissue macrophages, Biology, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Insulin resistance, VCO2, carbon dioxide production, FGF21, fibroblast growth factor, Internal medicine, UCP1, uncoupling protein 1, medicine, Empagliflozin, Animals, Hypoglycemic Agents, Obesity, Benzhydryl Compounds, Muscle, Skeletal, Sodium-Glucose Transporter 2 Inhibitors, ITT, insulin tolerance test, VO2, oxygen consumption, Inflammation, Macrophages, lcsh:R, SGLT, sodium/glucose cotransporter, Sodium glucose cotransporter-2 inhibitor, Body Weight, Insulin tolerance test, ALT, Alanine aminotransferase, Energy metabolism, UGE, urinary glucose excretion, Macrophage Activation, medicine.disease, BAT, brown adipose tissue, TC, total cholesterol, Fatty Liver, AMPK, AMP-activated protein kinase, Glucose, 030104 developmental biology, Endocrinology, Insulin Resistance, LMs, liver macrophages, Diet-induced obese, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c85fd9e3671e9effaeef0acf4b89dd1Test
https://doi.org/10.1016/j.ebiom.2017.05.028Test

المؤلفون: Wayne Bond Lau, Yan Lee, Huishou Zhao, Kun Lian, Wenjun Yan, Xiyao Chen, Shihao Zhao, Wei Wang, Jinglong Zhang, Ling Zhang, Fuyang Zhang, Feng Yan, Cheng Peng, Ling Tao, Chao Gao, Yunlong Xia, Xin-Liang Ma

المصدر: EBioMedicine, Vol 13, Iss C, Pp 157-167 (2016)
EBioMedicine

مصطلحات موضوعية: Male, AMP-Activated Protein Kinases, TNF-α, tumor necrosis factor-α, Mice, HFD, high fat diet, HSL, hormone sensitive lipase, AMP-activated protein kinase, AST, aspartate transaminase, BCKD, branched-chain α-ketoacid dehydrogenase, IL-6, interleukin-6, TUNEL, terminal deoxynucleotidyl transferased UTP nick end labeling, Liver injury, TG, triglyceride, TOR Serine-Threonine Kinases, Branched chain amino acids, IRS1, insulin receptor substrate-1, General Medicine, DGAT1, diacylglycerol acyltransferase-1, lcsh:Medicine (General), Lipotoxicity, medicine.medical_specialty, IL-1β, interleukin-1β, NASH, non-alcoholic steatohepatitis, Lipolysis, mTOR, mammalian target of rapamycin, SEM, standard error of the mean, Diet, High-Fat, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, IU, international unit, TGF-β, transforming growth factor-β, GFP-LC3, green fluorescent protein-light chain-3, BCKA, branched chain α-ketoacids, MDA, malondialdehyde, lcsh:R, β-AR, β-adrenergic receptor, OA, oleic acid, medicine.disease, BCAA, branched chain amino acids, 030104 developmental biology, Endocrinology, chemistry, siRNA, small interfering RNA, PKA, protein kinase A, Amino Acids, Branched-Chain, Blood Glucose, 0301 basic medicine, FASN, fatty acid synthase, Mice, Obese, lcsh:Medicine, chemistry.chemical_compound, Liver Function Tests, DG, diacylglycerol, Adipocytes, FFA, free fatty acids, ANOVA, analysis of variance, BDK, branched-chain α-ketoacid dehydrogenase kinase, lcsh:R5-920, AMPK, adenosine monophosphate-activated protein kinase, Mammalian target of rapamycin, biology, ND, normal diet, Fatty liver, MCP-1, monocyte chemotactic protein-1, cAMP, cyclic adenosine monophosphate, HPLC, high performance liquid chromatography, Lipogenesis, GTT, glucose tolerance test, SREBP-1c, sterol regulatory element binding protein-1c, Research Paper, NAFLD, non-alcoholic fatty liver disease, Normal diet, ELOVL6, elongation of very long chain fatty acids protein-6, HOMA-IR, homeostasis model assessment of insulin resistance, PP2Cm, protein phosphatase-2Cm, Hyperlipidemias, Mice, Transgenic, ISO, isoprenaline, Diabetes Mellitus, Experimental, ROS, reactive oxygen species, HE, hematoxylin-eosin, ALT, alanine aminotransferase, SOD, superoxide dismutase, 3T3-L1 Cells, Internal medicine, Autophagy, medicine, Animals, ACC, acetyl-coA carboxylase, ITT, insulin tolerance test, ATGL, adipose triglyceride lipase, Triglyceride, Body Weight, SCD1, stearoyl-CoA desaturase-1, IP, intraperitoneal injection, Disease Models, Animal, Hepatocytes, biology.protein, BSA, bovine serum albumin, Non-alcoholic fatty liver disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ed5eb12a69790abfde563ef0de6601Test