دورية أكاديمية
Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage
| العنوان: | Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage |
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| المؤلفون: | Rodrigo Salinas, Ramón, Libuy, Matías, Feliú, Felipe, Hasson, Daniel |
| المصدر: | Disease Markers |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2013 |
| المجموعة: | Universidad de Chile: Repositorio académico |
| مصطلحات موضوعية: | Molecular Biology, Genetics, Clinical Biochemistry, Biochemistry (medical) |
| الوصف: | Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, with hypertension being a major risk factor. Numerous studies support the contribution of reactive oxygen and nitrogen species in the pathogenesis of hypertension, as well as other pathologies associated with ischemia/ reperfusion. However, the validation of oxidative stress-related biomarkers in these settings is still lacking and novel association of these biomarkers and other biomarkers such as endothelial progenitor cells, endothelial microparticles, and ischemia modified albumin, is just emerging. Oxidative stress has been suggested as a pathogenic factor and therapeutic target in early stages of essential hypertension. Systolic and diastolic blood pressure correlated positively with plasma F2-isoprostane levels and negatively with total antioxidant capacity of plasma in hypertensive and normotensive patients. Cardiac surgery with extracorporeal circulation causes an ischemia/reperfusion event associ |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 18758630 02780240 |
| العلاقة: | Disease Markers, Volumen 35, Issue 6, 2018, Pages 773-790; https://repositorio.uchile.cl/handle/2250/166125Test |
| DOI: | 10.1155/2013/974358 |
| الإتاحة: | https://doi.org/10.1155/2013/974358Test https://repositorio.uchile.cl/handle/2250/166125Test |
| حقوق: | Attribution-NonCommercial-NoDerivs 3.0 Chile ; http://creativecommons.org/licenses/by-nc-nd/3.0/clTest/ |
| رقم الانضمام: | edsbas.D13CA7A6 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 18758630 02780240 |
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| DOI: | 10.1155/2013/974358 |