Microinflammation Factors in the Common Diseases of the Heart and Kidneys
| العنوان: | Microinflammation Factors in the Common Diseases of the Heart and Kidneys |
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| المؤلفون: | Danijela Tasic, Marina Deljanin Ilic, Gordana Kocic, Aleksandra Ignjatović, Sonja Radenkovic |
| المصدر: | Disease Markers, Vol 2015 (2015) Disease Markers |
| بيانات النشر: | Hindawi Limited, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Article Subject, Clinical Biochemistry, Inflammation, Cardiorenal syndrome, Biology, Gastroenterology, chemistry.chemical_compound, Cardio-Renal Syndrome, Internal medicine, Plasminogen Activator Inhibitor 1, Genetics, medicine, otorhinolaryngologic diseases, Humans, Molecular Biology, Aged, Kidney, lcsh:R5-920, Biochemistry (medical), C-reactive protein, Interleukin-8, Case-control study, General Medicine, Middle Aged, medicine.disease, Endocrinology, medicine.anatomical_structure, C-Reactive Protein, chemistry, Plasminogen activator inhibitor-1, Case-Control Studies, biology.protein, Female, medicine.symptom, Lipoproteins, HDL, lcsh:Medicine (General), Plasminogen activator, Research Article |
| الوصف: | Aim. To determine levels of interleukin-8 (IL-8) and plasminogen activator inhibitor-1 (PAI-1) in different cardiorenal syndrome (CRS) modalities and to compare findings to some already investigated direct and indirect parameters of inflammation and atherosclerosis.Materials and Methods. Testing involved 114 examinees, divided into control and clinical groups suffering from different modalities and were formed according to the basis of a valid classification for CRS.Results. C-reactive protein (CRP) was significantly higher in all CRSs in comparison to the control groupP<0.05. PAI-1 in CRSs was statistically higher than in the control group. IL-8 was increased in all CRSs, and especially in CRS-5, where no significance was found. PAI-1 correlated with IL-8 in all CRSs, with significant value in CRS-2 and CRS-5. Correlation for PAI-1 and high-density lipoproteins (HDL) was found in CRS-4, while IL-8 was found to be related to CRP level in all CRSs, with significance only in CRS-1P<0.001.Conclusions. C-reactive protein, IL-8, and PAI-1 could be useful for clinical differentiation of chronic modalities of CRSs. Inflammation was the most pronounced in CRS-4. Lipid status parameters could be useful for differentiation of CRSs. Furthermore, HDL in chronic primary kidney diseases and triglycerides and total cholesterol in CRS-5 could be valuable. |
| وصف الملف: | text/xhtml |
| اللغة: | English |
| تدمد: | 1875-8630 0278-0240 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e5c23cf45e1e82fefbf4c50eb31860Test https://doaj.org/article/11757ba525e54828a4ab962f6e1829beTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....50e5c23cf45e1e82fefbf4c50eb31860 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18758630 02780240 |
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