Clinical trials and meta-analyses of trials are models of clinical reality. A pharmacoeconomic model is a logical, quantitative blend of therapeutic and/or disease management strategies, evidence-based clinical outcomes, patient survival data and/or quality-of-life (utility) data, epidemiological data and costs. Pharmacoeconomic models can link evidence-based medicine to the local environment. They require locally appropriate resource consumption and cost information, so that the economic outcomes (e.g. cost and cost-effectiveness of therapy) are current and locally relevant.
