التفاصيل البيبلوغرافية
| العنوان: |
Large-scale evaluation of a rapid diagnostic test for human cystic echinococcosis. |
| المؤلفون: |
Baraquin, Alice1, Zait, Houria2, Grenouillet, Florence-Elisabeth3, Moreau, Elise3, Hamrioui, Boussad2, Grenouillet, Frédéric1,3 fgrenouillet@chu-besancon.fr |
| المصدر: |
Diagnostic Microbiology & Infectious Disease. Sep2017, Vol. 89 Issue 1, p20-25. 6p. |
| مصطلحات موضوعية: |
*DIAGNOSIS of Echinococcosis, *ZOONOSES, *CROSS reactions (Immunology), *ROUTINE diagnostic tests, *SEROLOGY |
| مستخلص: |
Cystic echinococcosis (CE) is a neglected zoonotic disease, diagnosed through clinical findings, imaging techniques, and serology, for which many serological tests are available. Here we report a rapid unit assay, the immunochromatographic VIRapid® HYDATIDOSIS test (Vircell, Granada, Spain), potentially suitable for laboratories in low-prevalence or poorly equipped areas. This test was evaluated with a large retrospective cohort (224 sera), including patients suffering from CE or from other parasitic or liver diseases. The test was also assessed in routine conditions with a prospective cohort (115 sera) in areas where both cystic and alveolar echinococcoses have been diagnosed. Its performance (in terms of sensitivity, specificity, and both positive and negative likelihood ratios) was similar to an ELISA based on a crude antigen. Our study shows that this test performs adequately in the diagnostic process, when used with caution, especially regarding cross-reactivity with other parasitic diseases. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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