التفاصيل البيبلوغرافية
| العنوان: |
Genetic Determinants of Diabetic Nephropathy in Type 2 Diabetes. |
| المؤلفون: |
Veves, Aristidis, Cortes, Pedro, Mogensen, Carl Erik, Placha, Grzegorz, Krolewski, Andrzej S. |
| المصدر: |
Diabetic Kidney; 2006, p329-350, 22p |
| مستخلص: |
Diabetic nephropathy (DN) contributes significantly to morbidity and premature mortality in diabetes mellitus (1,2). Whereas the identification of specific environmental factors involved in the development of proteinuria and progressively declining kidney function have led to clinical measures that modify the natural history of the disease (3,4), available interventions (primarily blood glucose control and treatment with renoprotective and antihypertensive drugs) fall short of the ultimate goal of eradicating this complication. The severity of this deficiency is highlighted best by the fact that an epidemic of end-stage renal disease (ESRD) has developed over the past 20 yr, particularly in patients with type 2 diabetes mellitus (T2DM) in the United States, without any signs of leveling off (5). With T2DM becoming more common among young adults and in pediatric populations (6), one may infer that the burden of ESRD in the US population will increase even further unless more effective clinical measures are found. [ABSTRACT FROM AUTHOR] |
|
Copyright of Diabetic Kidney is the property of Springer eBooks and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Supplemental Index |
