The Accuracy and Efficacy of Real-Time Continuous Glucose Monitoring Sensor in Chinese Diabetes Patients: A Multicenter Study

التفاصيل البيبلوغرافية
العنوان: The Accuracy and Efficacy of Real-Time Continuous Glucose Monitoring Sensor in Chinese Diabetes Patients: A Multicenter Study
المؤلفون: Yuqian Bao, Xiaofeng Lv, Jinxiao Wu, Jing Li, Xingguang Zhang, Yiming Mu, Xianling Wang, Weiping Jia, Jian Zhou
المصدر: Diabetes Technology & Therapeutics. 14:710-718
بيانات النشر: Mary Ann Liebert Inc, 2012.
سنة النشر: 2012
مصطلحات موضوعية: Adult, Blood Glucose, Male, Insulin pump, China, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Monitoring, Ambulatory, Hypoglycemia, Young Adult, Insulin Infusion Systems, Endocrinology, Asian People, Reference Values, Jian Zhou, Blood Glucose Self-Monitoring, Diabetes mellitus, medicine, Humans, Prospective Studies, Prospective cohort study, Aged, business.industry, Reproducibility of Results, Equipment Design, Original Articles, Venous blood, Middle Aged, medicine.disease, Confidence interval, Surgery, Medical Laboratory Technology, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hyperglycemia, Anesthesia, Female, business
الوصف: The purpose of this multicenter study was to investigate the accuracy of a real-time continuous glucose monitoring sensor in Chinese diabetes patients.In total, 48 patients with type 1 or 2 diabetes from three centers in China were included in the study. The MiniMed Paradigm(®) 722 insulin pump (Medtronic, Northridge, CA) was used to monitor the real-time continuous changes of blood glucose levels for three successive days. Venous blood of the subjects was randomly collected every 15 min for seven consecutive hours on the day when the subjects were wearing the sensor. Reference values were provided by the YSI(®) 2300 STAT PLUS™ glucose and lactate analyzer (YSI Life Sciences, Yellow Springs, OH).In total, 1,317 paired YSI-sensor values were collected from the 48 patients. Of the sensor readings, 88.3% (95% confidence interval, 0.84-0.92) were within±20% of the YSI values, and 95.7% were within±30% of the YSI values. Clarke and consensus error grid analyses showed that the ratios of the YSI-sensor values in Zone A to the values in Zone B were 99.1% and 99.9%, respectively. Continuous error grid analysis showed that the ratios of the YSI-sensor values in the region of accurate reading, benign errors, and erroneous reading were 96.4%, 1.8%, and 1.8%, respectively. The mean absolute relative difference (ARD) for all subjects was 10.4%, and the median ARD was 7.8%. Bland-Altman analysis detected a mean blood glucose level of 3.84 mg/dL. Trend analysis revealed that 86.1% of the difference of the rates of change between the YSI values and the sensor readings occurred within the range of 1 mg/dL/min.The Paradigm insulin pump has high accuracy in both monitoring the real-time continuous changes and predicting the trend of changes in blood glucose level. However, actual clinical manifestations should be taken into account for diagnosis of hypoglycemia.
تدمد: 1557-8593
1520-9156
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c4892bf5f7313130683c39a4c352d6Test
https://doi.org/10.1089/dia.2012.0014Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....b5c4892bf5f7313130683c39a4c352d6
قاعدة البيانات: OpenAIRE