Abdominal adiposity and cardiovascular risk factors in adolescents with type 1 diabetes
| العنوان: | Abdominal adiposity and cardiovascular risk factors in adolescents with type 1 diabetes |
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| المؤلفون: | Valerio, G, Iafusco, D, Zucchini, S, Maffeis, C, Study Group on Diabetes of Italian Society of Pediatric Endocrinology, Collaborators: Lera R, D. i. a. b. e. t. o. l. o. g. y., Cherubini, V, Biagioni, M, Rollo, A, Gallo, F, Toni, S, Guasti, M, Mammì, F, Bruzzese, M, Lombardo, F, Salzano, G, Scaramuzza, A, Zuccotti, Gv, Sacco, H, Iughetti, L, Predieri, B, Calcaterra, V, Federico, G, Marchi, B, Cerutti, Franco, Rabbone, I, Cardinale, G, De Berardinis, F, De Donno, V, Franzese, A, Mozzillo, E, Prisco, F, Zedda, Ma, Ripoli, C. |
| المساهمون: | Valerio, G., Iafusco, D., Zucchini, S., Maffeis, C., Lera, R., Cherubini, V., Biagioni, M., Rollo, A., Gallo, F., Toni, S., Guasti, M., Mammi, F., Bruzzese, M., Lombardo, F., Salzano, G., Scaramuzza, A., Zuccotti, G. V., Iughetti, L., Predieri, B., Calcaterra, V., Federico, G., Marchi, B., Cerutti, F., Rabbone, I., Cardinale, G., De Berardinis, F., De Donno, V., Franzese, A., Mozzillo, Enza., Prisco, F., Zedda, M. A., Ripoli, C., Valerio, G, Iafusco, Dario, Zucchini, S, Maffeis, C, The Study Group on Diabetes of the Italian Society of Pediatric, Endocrinology, Diabetology |
| المصدر: | Università degli Studi del Piemonte Orientale-IRIS |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | cardiovascular risk factors, Blood Glucose, Male, obesity, Health Knowledge, Attitudes, Practice, Glycated Hemoglobin A, type 1 diabetes, Endocrinology, Diabetes and Metabolism, Overweight, chemistry.chemical_compound, Endocrinology, Risk Factors, Prevalence, Abdominal obesity, Body surface area, Metabolic Syndrome, General Medicine, childre, Italy, Obesity, Abdominal, Hypertension, Female, medicine.symptom, Cardiovascular risk, Metabolic syndrome, Type 1 diabetes, Human, medicine.medical_specialty, Type 1 diabete, Adolescent, abdominal fat, Diabetic Angiopathie, Diabetes mellitus, Internal medicine, Weight Loss, Internal Medicine, medicine, Humans, Risk factor, Sex Distribution, Glycated Hemoglobin, business.industry, Risk Factor, medicine.disease, Surgery, Diabetes Mellitus, Type 1, chemistry, Glycated hemoglobin, business, Diabetic Angiopathies |
| الوصف: | Aim To analyze the prevalence of abdominal adiposity and other traditional risk factors for cardiovascular disease in a large sample of Italian adolescents with type 1 diabetes mellitus (T1DM). Methods T1DM adolescents ( n =412 age: 17.3±0.9years) were enrolled from 18 clinical centres. Anthropometric and laboratory parameters, blood pressure and data on insulin treatment were registered. Metabolic syndrome (MetSy) was defined according to the International Diabetes Federation criteria. Results Abdominal obesity was the most common risk factor (20.1%) in females, while hypertension in males (25.1%). MetSy was found in 9.5% patients, predominantly in females. Patients with MetSy exhibited higher insulin requirement per body surface area and higher glycated hemoglobin than patients without MetSy. Overweight/obese patients had a much higher prevalence of MetSy than normal weight patients. The logistic regression analysis showed that just waist-to-height ratio and insulin dose per body surface area contributed to discriminate subjects with the MetSy from those without. Conclusion Adolescence is a critical period in determining risk of future vascular complications in T1DM. Pediatric diabetologists need to be aware of the considerable occurrence of abdominal adiposity and MetSy in T1DM patients, particularly in females, and should make any effort to achieve normal weight and better health outcomes. |
| تدمد: | 1872-8227 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04586c7efa7c4fbd46f7a3fd52ca16b4Test https://pubmed.ncbi.nlm.nih.gov/22336634Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....04586c7efa7c4fbd46f7a3fd52ca16b4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18728227 |
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