Treatment with Human Insulin (recombinant DNA) in Diabetic Subjects Pretreated with Pork or Beef Insulin: First Results of a Multicenter Study
| العنوان: | Treatment with Human Insulin (recombinant DNA) in Diabetic Subjects Pretreated with Pork or Beef Insulin: First Results of a Multicenter Study |
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| المؤلفون: | J Beyer, F Enzmann, M Lauerbach, P Althoff, W Bachmann, K Brandstetter, U Cordes, A Dannehl, G Düntsch, R Haas, K Heun, L Kerp, N Lotz, H Mehnert, H-J Mitzkat, K Petersen, C Rosak, D Sailer, K Schlüter, K Schöffling, K E Schröder, P Schumm, T Weber |
| المصدر: | Diabetes Care. 5:140-148 |
| بيانات النشر: | American Diabetes Association, 1982. |
| سنة النشر: | 1982 |
| مصطلحات موضوعية: | Adult, Blood Glucose, medicine.medical_specialty, Swine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Insulin, Isophane, NPH insulin, law.invention, Double-Blind Method, law, Internal medicine, Diabetes mellitus, Internal Medicine, Human insulin, Animals, Humans, Insulin, Medicine, Aged, Advanced and Specialized Nursing, Clinical Trials as Topic, business.industry, Middle Aged, medicine.disease, Recombinant Proteins, Diabetes Mellitus, Type 1, Endocrinology, Postprandial, Metabolic control analysis, Recombinant DNA, Cattle, business, Beef insulin |
| الوصف: | In two double-blind studies 66 insulin-dependent diabetic subjects pretreated with pork insulin were changed to human insulin (recombinant DNA) or a purified pork insulin preparation (regular and NPH insulin). Sixty-five patients previously pretreated with beef insulin were transferred, in a randomized, double-blind fashion, to human insulin and purified beef insulin of the same preparations (regular and NPH insulin). Patients’ metabolic control, as demonstrated by fasting and 1-h postprandial blood glucose, HbA1c, and daily insulin dosage, over 4 mo was unchanged in our four groups compared with the values before changing insulin preparation. No severe hypoglycemic attacks or skin reactions were reported. |
| تدمد: | 1935-5548 0149-5992 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6f042465e6cd59cea34b5d3001b920Test https://doi.org/10.2337/diacare.5.2.s140Test |
| رقم الانضمام: | edsair.doi.dedup.....2f6f042465e6cd59cea34b5d3001b920 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19355548 01495992 |
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