Effects of periodontal therapy on glucose management in people with diabetes mellitus
| العنوان: | Effects of periodontal therapy on glucose management in people with diabetes mellitus |
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| المؤلفون: | Francesco D'Aiuto, Kalpesh Patel, N. Calabrese, M. Massi-Benedetti, A. Calabrese, G. Calabrese |
| المصدر: | Diabetes & Metabolism. 37:456-459 |
| بيانات النشر: | Elsevier BV, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Adult, Blood Glucose, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Population, Dentistry, Oral Health, Disease, Cohort Studies, Young Adult, Endocrinology, Insulin resistance, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, Child, education, Periodontal Diseases, Aged, Glycated Hemoglobin, Periodontitis, education.field_of_study, business.industry, General Medicine, Middle Aged, medicine.disease, Glucose management, Diabetes Mellitus, Type 1, Treatment Outcome, Diabetes Mellitus, Type 2, Cohort, business, Body mass index, Follow-Up Studies |
| الوصف: | The primary aim of this study was to examine the effects of intensive periodontal therapy on HbA(1c) in a mixed diabetes mellitus (DM) (types 1 and 2) population with moderate periodontitis (PD).A total of 93 subjects with PD and DM, recruited from referrals to the Department of Endocrinology at the Perugia Hospital, were included in a follow-up cohort clinical study comprising two parallel periodontal therapy groups-one receiving intensive periodontal therapy (IPT, n=44) and the other serving as controls (CPT, n=49)-with an 8-month follow-up. Clinical periodontal examinations and blood samples were collected 4 and 8 months after the completion of therapy.The IPT group presented with greater reductions of all periodontal indices compared with the CPT group at both follow-ups (P0.001). Whereas, after 4 months, there were no major differences in HbA(1c) levels between groups, after 8 months, the IPT group presented with a 0.57% (95% CI: 0.12 to 1.09) greater reduction in HbA(1c) than the CPT group (P=0.03). This reduction was independent of age, gender, smoking and body mass index. However, the difference in HbA(1c) was greater in individuals with type 2 DM (0.95% reduction, 95% CI: 0.32 to 1.58; P=0.004) compared with those with type 1 DM.IPT resulted in greater improvement of gingival health in patients with DM. Improved oral health in those with type 2 DM may have an effect on medium-term glucose management and could possibly lead to long-term health benefits. (ISRCTN00559156). |
| تدمد: | 1262-3636 0055-9156 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd657f7c7e657da2744b9ade9a03844bTest https://doi.org/10.1016/j.diabet.2011.05.004Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....cd657f7c7e657da2744b9ade9a03844b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 12623636 00559156 |
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