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1
المؤلفون: Lorenzo Piemonti, Rita Nano, Nicholas C. Vierra, Gareth G. Lavery, Piero Marchetti, David J. Hodson, Craig L. Doig, David A. Jacobson, Marco Bugliani, Nicholas H. F. Fine, Guy A. Rutter, Yasir S Elhassan
المساهمون: Pathology/molecular and cellular medicine, Fine, Nicholas H. F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J., Diabetes UK, Medical Research Council (MRC), European Foundation for the Study of Diabetes
المصدر: Diabetes. 67(2)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cell signaling, Hydrocortisone, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Mice, Inbred Strains, Carbohydrate metabolism, Article, Tissue Culture Techniques, Endocrinology & Metabolism, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Downregulation and upregulation, Corticosterone, Internal medicine, Insulin-Secreting Cells, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Insulin Secretion, medicine, Internal Medicine, Cyclic AMP, Animals, Humans, Insulin, Calcium Signaling, Glucocorticoids, Mice, Knockout, Chemistry, Cell Differentiation, 11 Medical And Health Sciences, Cortisone, Kinetics, 030104 developmental biology, Endocrinology, Glucose, Lipotoxicity, Calcium Channels, Homeostasis, Glucocorticoid, Biomarkers, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3167d9071cd9a516dc05c6cadf91d7Test
https://pubmed.ncbi.nlm.nih.gov/29203512Test -
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المؤلفون: Jiandie D. Lin, Lei Yu, Matthew M. Molusky, Siming Li, Di Ma
المصدر: Diabetes
مصطلحات موضوعية: medicine.medical_specialty, Adipose Tissue, White, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Carbohydrate metabolism, Polymerase Chain Reaction, Gene Expression Regulation, Enzymologic, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Endopeptidases, Internal Medicine, medicine, Insulin, Glucose homeostasis, Animals, RNA, Messenger, Muscle, Skeletal, Cells, Cultured, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Gene knockdown, Gluconeogenesis, Metabolism, Circadian Rhythm, Mice, Inbred C57BL, Endocrinology, Glucose, Liver, Hepatocytes, Commentary, RNA Interference, Ubiquitin-Specific Proteases, Signal transduction, Food Deprivation, Ubiquitin Thiolesterase, 030217 neurology & neurosurgery, Glucocorticoid, Signal Transduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f52d3ab974f6ee321d32ceeb618b7Test
http://europepmc.org/articles/PMC3331773Test -
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المؤلفون: Brian R. Walker, Scott P. Webster, Donald R. Dunbar, Nicholas M. Morton, X. Liu, Sophie Turban, Lynne Ramage, John J. Mullins, Jonathan R. Seckl
المصدر: Diabetes
Turban, S, Liu, X, Ramage, L, Webster, S P, Walker, B R, Dunbar, D R, Mullins, J J, Seckl, J R & Morton, N M 2012, ' Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism That Prevents High-Fat Diet–Induced β-Cell Failure ', Diabetes, vol. 61, no. 3, pp. 642-652 . https://doi.org/10.2337/db11-1054Testمصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Palmitic Acid, 030209 endocrinology & metabolism, Type 2 diabetes, Biology, Diet, High-Fat, Mice, 03 medical and health sciences, 0302 clinical medicine, 11β-hydroxysteroid dehydrogenase type 1, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Insulin Secretion, Diabetes Mellitus, Internal Medicine, medicine, Animals, Insulin, Extracellular Signal-Regulated MAP Kinases, 030304 developmental biology, Online Letters to the Editor, 0303 health sciences, Glucose tolerance test, medicine.diagnostic_test, Pancreatic islets, Glucose Tolerance Test, medicine.disease, Cyclic AMP-Dependent Protein Kinases, 3. Good health, Insulin oscillation, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 2, biology.protein, Metabolic syndrome, hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0008c5960a9e368dd9d4c0e5c658acbTest
https://doi.org/10.2337/db11-1054Test -
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المؤلفون: Stephen G. Hillier, Eberhard Fuchs, Victor W. Armstrong, Moffat J. Nyirenda, Frank Streit, Roderick N. Carter, Jonathan R. Seckl, Annick de Vries, Justin I Tang, Christina Schlumbohm, Michael Oellerich
المصدر: Diabetes
Nyirenda, M J, Carter, R, Tang, J I, de Vries, A, Schlumbohm, C, Hillier, S G, Streit, F, Oellerich, M, Armstrong, V W, Fuchs, E & Seckl, J R 2009, ' Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11 beta-Hydroxysteroid Dehydrogenase Type 1 ', Diabetes, vol. 58, no. 12, pp. 2873-2879 . https://doi.org/10.2337/db09-0873Testمصطلحات موضوعية: Blood Glucose, Aging, medicine.medical_specialty, Time Factors, Offspring, Endocrinology, Diabetes and Metabolism, Adipose tissue, Biology, Polymerase Chain Reaction, Pathophysiology, Dexamethasone, Gene Expression Regulation, Enzymologic, Glucocorticoid receptor, Pregnancy, 11β-hydroxysteroid dehydrogenase type 1, Internal medicine, biology.animal, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Internal Medicine, medicine, Animals, Glucocorticoids, Triglycerides, Metabolic Syndrome, Fetus, Marmoset, Callithrix, medicine.disease, Up-Regulation, Endocrinology, Adipose Tissue, Prenatal Exposure Delayed Effects, biology.protein, Female, Original Article, Metabolic syndrome, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361d19b0347ad6e1171c9b2df46cb27fTest
https://doi.org/10.2337/db09-0873Test -
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المؤلفون: David M. Smith, Jeremy W. Tomlinson, Mark Sherlock, David Laber, Gareth G. Lavery, Paul M. Stewart, Alice Yu, Iwona J. Bujalska, Laura Gathercole, Jaswinder K. Sethi, Krisztina Hegyi, Carol Lenaghan, Rachel M. Mayers, Gemma Convey, Stuart A. Morgan
المصدر: Diabetes
مصطلحات موضوعية: medicine.medical_specialty, QH301 Biology, Endocrinology, Diabetes and Metabolism, Glucose uptake, medicine.medical_treatment, 030209 endocrinology & metabolism, Deoxyglucose, Polymerase Chain Reaction, Dexamethasone, Cell Line, Myoblasts, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin resistance, 11β-hydroxysteroid dehydrogenase type 1, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Internal Medicine, medicine, Myocyte, Animals, Humans, Insulin, RNA, Messenger, Muscle, Skeletal, Protein kinase B, Glucocorticoids, Cells, Cultured, 030304 developmental biology, 0303 health sciences, biology, Reverse Transcriptase Polymerase Chain Reaction, Skeletal muscle, medicine.disease, IRS1, Kinetics, medicine.anatomical_structure, Endocrinology, Metabolism, RC Internal medicine, biology.protein, RNA, Original Article, Insulin Resistance, hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337f5b847e426b3920c121bd98410ff2Test
http://europepmc.org/articles/PMC2768185Test -
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المؤلفون: Ruth Andrew, Ken R. Smith, Robert Andrews, Natalie Z.M. Homer, Brian R. Walker, Thekkepat C. Sandeep
المصدر: Diabetes. 54:872-879
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Hydrocortisone, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Carbenoxolone, Adipose tissue, White adipose tissue, Double-Blind Method, 11β-hydroxysteroid dehydrogenase type 1, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Internal Medicine, Hyperinsulinemia, Humans, Insulin, Medicine, Obesity, Cross-Over Studies, biology, business.industry, Middle Aged, medicine.disease, Cortisone, Endocrinology, Adipose Tissue, biology.protein, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8da51c21699c20a6035fcaaad3b3031Test
https://doi.org/10.2337Test/diabetes .54.3.872 -
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المؤلفون: Pinky V. Tripathi, Theodore C. Friedman, Ying Wang, Kabirullah Lutfy, Yuichi Nakagawa, Yanjun Liu, Reiko Sakurai
المصدر: Diabetes. 54:32-40
مصطلحات موضوعية: Male, medicine.medical_specialty, Transcription, Genetic, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Mice, Obese, Biology, Mice, chemistry.chemical_compound, Receptors, Glucocorticoid, Glucocorticoid receptor, Insulin resistance, Corticosterone, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Internal Medicine, medicine, Animals, RNA, Messenger, Receptor, Cells, Cultured, Insulin, medicine.disease, Mifepristone, Glucose, Phenotype, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 2, Gene Expression Regulation, chemistry, Hepatocyte, Hepatocytes, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, Hormone, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e399a4e88bbb5f0317edfff3049ff98Test
https://doi.org/10.2337Test/diabetes .54.1 .32 -
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المؤلفون: Daniel Flanagan, Christopher B. Whorwood, Stephen J. Donovan, David I. W. Phillips, Christopher D. Byrne
المصدر: Diabetes. 51:1066-1075
مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Blood Pressure, Biology, Culture Media, Serum-Free, Gene Expression Regulation, Enzymologic, Body Mass Index, Cell Fusion, Receptors, Glucocorticoid, Glucocorticoid receptor, Insulin resistance, Hyperinsulinism, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Internal Medicine, medicine, Humans, Insulin, Muscle, Skeletal, Cells, Cultured, Metabolic Syndrome, Hydroxysteroid Dehydrogenases, Glucose clamp technique, medicine.disease, Immunohistochemistry, Kinetics, Endocrinology, Gene Expression Regulation, Glucose Clamp Technique, Metabolic syndrome, Cortisone, DNA Probes, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2ace999c9a13899398fad576538180Test
https://doi.org/10.2337Test/diabetes .51.4.1066 -
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المؤلفون: Brian R. Walker, Dhiraj Tripathi, Norma C. McAvoy, Ruth Andrew, Roland H Stimson, Peter C. Hayes
المصدر: Diabetes
Stimson, R H, Andrew, R, McAvoy, N C, Tripathi, D, Hayes, P C & Walker, B R 2011, ' Increased Whole-Body and Sustained Liver Cortisol Regeneration by 11 beta-Hydroxysteroid Dehydrogenase Type 1 in Obese Men With Type 2 Diabetes Provides a Target for Enzyme Inhibition ', Diabetes, vol. 60, no. 3, pp. 720-725 . https://doi.org/10.2337/db10-0726Testمصطلحات موضوعية: Cortisol secretion, Adult, Male, medicine.medical_specialty, Hydrocortisone, Endocrinology, Diabetes and Metabolism, Adipose tissue, Type 2 diabetes, Dexamethasone, 11β-hydroxysteroid dehydrogenase type 1, Tandem Mass Spectrometry, Internal medicine, Diabetes mellitus, 11-beta-Hydroxysteroid Dehydrogenase Type 1, medicine, Internal Medicine, Humans, Obesity, Glucocorticoids, Chromatography, High Pressure Liquid, Aged, Analysis of Variance, biology, business.industry, Middle Aged, medicine.disease, Endocrinology, Metabolism, Diabetes Mellitus, Type 2, Liver, biology.protein, Body Composition, Cortisone, business, Glucocorticoid, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Chromatography, Liquid
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2311d8d32f7684daab33dd3290338f4eTest
https://pubmed.ncbi.nlm.nih.gov/21266326Test -
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المصدر: Diabetes. 57(3)
مصطلحات موضوعية: medicine.medical_specialty, Aging, Time Factors, Endocrinology, Diabetes and Metabolism, Adipose tissue, Adipokine, Biology, chemistry.chemical_compound, Glucocorticoid Sensitivity, Adipokines, Corticosterone, Internal medicine, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Glucose Intolerance, Internal Medicine, medicine, Animals, Rats, Wistar, Glucocorticoids, Inflammation, Adiponectin, Overweight, Dietary Fats, Diet, Rats, PPAR gamma, Endocrinology, chemistry, Adipose Tissue, Gene Expression Regulation, Liver, Resistin, Liver function, Insulin Resistance, Glucocorticoid, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1e80ad69a8e4fc1e78843e6362b587Test
https://pubmed.ncbi.nlm.nih.gov/18057089Test