نتائج البحث

1

Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes

المؤلفون: Liping Yu, Michael P. Morran, Dorothy J. Becker, Howard W. Davidson, Shuai Huang, Andrew D Vonberg, Massimo Pietropaolo, Charles F. Verge, Roberto Gianani, Maria Acevedo-Calado, Susan L. Pietropaolo, Stephen S. Rich, Carla J. Greenbaum, Santiago Schnell, Aaron W. Michels

المصدر: Diabetes

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Proband, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Biology, Epitope, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal Medicine, medicine, Humans, Receptor-Like Protein Tyrosine Phosphatases, Class 8, Child, Autoantibodies, Genetics, geography, Type 1 diabetes, geography.geographical_feature_category, Insulin, Haplotype, Autoantibody, Infant, Middle Aged, Islet, medicine.disease, Diabetes Mellitus, Type 1, 030104 developmental biology, Haplotypes, Child, Preschool, biology.protein, Female, Immunology and Transplantation, Antibody, HLA-DRB1 Chains

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5131e2d5c29a6f394031271fbb16c72bTest
https://doi.org/10.2337/db18-1351Test

2

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes

المؤلفون: Noa Weinberg-Corem, Yuval Dor, Sigurd Lenzen, Avital Swisa, Benjamin Glaser, Elad Horwitz, Knut Dahl-Jørgensen, Maya Fischman, Agnes Klochendler, Marcela Brissova, Anne Jörns, Sophia Zhitomirsky, Tsuria Lax, Lars Krogvold, Alvin C. Powers, Tehila Dahan, Noa Hurvitz

المصدر: Diabetes

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, endocrine system diseases, DNA repair, DNA damage, Endocrinology, Diabetes and Metabolism, Inflammation, medicine.disease_cause, Diabetes Mellitus, Experimental, Autoimmunity, Islets of Langerhans, Mice, Young Adult, 03 medical and health sciences, Insulin-Secreting Cells, Internal Medicine, medicine, Animals, Humans, Autoimmune disease, geography, geography.geographical_feature_category, business.industry, nutritional and metabolic diseases, Middle Aged, Islet, medicine.disease, Streptozotocin, Diabetes Mellitus, Type 1, 030104 developmental biology, Islet Studies, Cancer research, Female, medicine.symptom, business, Ex vivo, DNA Damage, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e3de0a054b8dcdf74d30d164591abaTest
https://doi.org/10.2337/db17-1006Test

3

Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells

المؤلفون: Li Xie, Subhankar Dolai, Edwin R. Chapman, Youhou Kang, Huanli Xie, Dan Zhu, Tao Liang, Herbert Y. Gaisano, Tairan Qin

المصدر: Diabetes

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, endocrine system, Calmodulin, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Synaptotagmin 1, Exocytosis, Synaptotagmins, Small hairpin RNA, Rats, Sprague-Dawley, 03 medical and health sciences, Glucagon-Like Peptide 1, Internal medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Animals, Humans, Insulin, Receptor, Aged, geography, geography.geographical_feature_category, Qa-SNARE Proteins, Secretory Vesicles, Imidazoles, Middle Aged, Islet, Cell biology, Rats, 030104 developmental biology, Endocrinology, Glucose, Islet Studies, biology.protein, Calcium, Female, SNARE Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a0f7b4af49a7b785cdea3ea97fba69Test
http://europepmc.org/articles/PMC5384637Test

4

Loss of IDO1 expression from human pancreatic β-cells precedes their destruction during the development of type 1 diabetes

المؤلفون: Ursula Grohmann, Giada Mondanelli, Nathaly Gonzalez, Lars Krogvold, Knut Dahl-Jørgensen, Jose Zapardiel Gonzalo, Teresa Rodriguez Calvo, Matthias von Herrath, Benoît Van den Eynde, Ciriana Orabona, Florence Anquetil

المصدر: Diabetes. 67(9)

مصطلحات موضوعية: 0301 basic medicine, Male, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Autoimmunity, medicine.disease_cause, Cohort Studies, 0302 clinical medicine, Insulin-Secreting Cells, Insulin, Young adult, Fluorescent Antibody Technique, Indirect, chemistry.chemical_classification, geography.geographical_feature_category, Middle Aged, Islet, Transport protein, Protein Transport, 030220 oncology & carcinogenesis, Disease Progression, Female, Adult, Adolescent, Down-Regulation, Pathophysiology, Autoimmune Diseases, Prediabetic State, 03 medical and health sciences, Young Adult, Downregulation and upregulation, Diabetes mellitus, Internal Medicine, medicine, Cadaver, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Aged, Autoantibodies, Type 1 diabetes, geography, business.industry, medicine.disease, 030104 developmental biology, Enzyme, Cross-Sectional Studies, Diabetes Mellitus, Type 1, chemistry, Diabetes Mellitus, Type 2, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9d26888a783466e850ba525f79ac16Test
http://ora.ox.ac.uk/objects/uuidTest:

5

Exocrine and Endocrine Interactions in Cystic Fibrosis: A Potential Key to Understanding Insulin Secretion in Health and Disease?

المؤلفون: Claudio Cobelli, Adrian Vella

المصدر: Diabetes

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Cystic Fibrosis, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Gastric Inhibitory Polypeptide, Disease, Biology, Pathophysiology, Incretins, Cystic fibrosis, Islets of Langerhans, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, In vivo, Commentaries, Insulin-Secreting Cells, Internal medicine, Internal Medicine, medicine, Humans, Insulin, Endocrine system, Secretion, Pancreas, geography, geography.geographical_feature_category, C-Peptide, Glucose Tolerance Test, Middle Aged, Glucagon, Islet, medicine.disease, Glucose, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Exocrine Pancreatic Insufficiency, Female, Proinsulin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194d931b9494ea7ef91d94234fc765b4Test
https://doi.org/10.2337/dbi16-0049Test

6

Interleukin-10+ Regulatory B Cells Arise Within Antigen-Experienced CD40+ B Cells to Maintain Tolerance to Islet Autoantigens

المؤلفون: Moufida Ben Nasr, Roberto Bassi, Sonja Kleffel, Andrea Vergani, Tobias Schatton, Monika A. Niewczas, Clive Wasserfall, Mohamed H. Sayegh, Francesca D'Addio, Paolo Fiorina, Mark A. Atkinson, Sara Tezza, Reza Abdi, Susan Wong, Kevin C. O’Connor, Li Wen

المصدر: Diabetes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeca7ceee1ae5069aa81e354361a54bbTest
https://doi.org/10.2337/db13-1639Test

7

Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit

المؤلفون: Masako Suzuki, Yoriko Nishida, Taro Maruyama, Shoichiro Tanaka, Hiroki Shimura, Sayaka Arai-Yamashita, Toyoshi Endo, Akio Kawaguchi, Masahiro Kaneshige, Akira Shimada, Daiichiro Akiyama, Ryohei Katoh, Masashi Takahashi, Kaoru Aida, Soichi Takizawa, Tetsuro Kobayashi, Fumihiko Furuya

المصدر: Diabetes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181ce142dedee35e2ac445f2d7db241aTest
http://europepmc.org/articles/PMC2750208Test

8

Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis

المؤلفون: Marika Bogdani, Nadine Nagy, Anthony J. Day, Paul L. Bollyky, Thomas N. Wight, Susan Potter-Perigo, Pamela Y. Johnson

المصدر: Diabetes

مصطلحات موضوعية: Aging, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Enteroendocrine cell, chemistry.chemical_compound, Versicans, 0302 clinical medicine, Hyaluronic acid, Insulin, Hyaluronic Acid, Child, 0303 health sciences, geography.geographical_feature_category, biology, Middle Aged, Islet, 3. Good health, Hyaluronan Receptors, medicine.anatomical_structure, Child, Preschool, Versican, medicine.symptom, Adult, endocrine system, medicine.medical_specialty, Lymphoid Tissue, 030209 endocrinology & metabolism, Inflammation, Islets of Langerhans, 03 medical and health sciences, Internal medicine, Alpha-Globulins, Internal Medicine, medicine, Humans, Aged, 030304 developmental biology, geography, Pancreatic islets, Infant, Germinal center, medicine.disease, Diabetes Mellitus, Type 1, Endocrinology, Islet Studies, Gene Expression Regulation, chemistry, Case-Control Studies, biology.protein, Cell Adhesion Molecules, Insulitis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e969a6faf34931f8524cf9156fee4eTest
https://doi.org/10.2337/db13-1658Test

9

Insulin Resistance Alters Islet Morphology in Nondiabetic Humans

المؤلفون: Rohit N. Kulkarni, Alfredo Pontecorvi, Gian Pio Sorice, Andrea Giaccari, Gennaro Clemente, Jens J. Holst, Giovanna Muscogiuri, Jiang Hu, Teresa Mezza

المساهمون: Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, J. J., Giaccari, A., Kulkarni, R. N.

المصدر: Diabetes

مصطلحات موضوعية: Male, insulin secretion, transdifferentiation, transdifferenziazione, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Glucose uptake, secrezione insulinica, Type 2 diabetes, neogenesi, Glucagon-Like Peptide 1, Insulin-Secreting Cells, geography.geographical_feature_category, isole pancreatiche, Middle Aged, Islet, Insulin oscillation, medicine.anatomical_structure, insulino resistenza, Female, Glucagon-Secreting Cell, neogenesis, Human, Adult, medicine.medical_specialty, Incretin, Biology, Islets of Langerhans, Pancreatectomy, Insulin resistance, beta cellule, Internal medicine, Internal Medicine, medicine, Humans, Aged, geography, Hyperplasia, pancreatic islets, Insulin, Pancreatic islets, Islets of Langerhan, Settore MED/13 - ENDOCRINOLOGIA, medicine.disease, beta cells, Endocrinology, Islet Studies, Glucagon-Secreting Cells, Insulin-Secreting Cell, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1145e717731d2908b39e2d0b6181cbeTest
http://europepmc.org/articles/PMC3931397Test

10

Intrahepatic Transplanted Islets in Humans Secrete Insulin in a Coordinate Pulsatile Manner Directly Into the Liver

المؤلفون: Peter C. Butler, Antoinette Moran, Ryan Galasso, Johannes D. Veldhuis, Juris J. Meier, Bernhard J. Hering, Irene Hong-McAtee

المصدر: Diabetes. 55:2324-2332

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1fd295625832788fa763b8247afee4Test
https://doi.org/10.2337/db06-0069Test

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