دورية أكاديمية
Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis.
| العنوان: | Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis. |
|---|---|
| المؤلفون: | Brott, Thomas G, Howard, George, Roubin, Gary S, Meschia, James F, Mackey, Ariane, Brooks, William, Moore, Wesley S, Hill, Michael D, Mantese, Vito A, Clark, Wayne M, Timaran, Carlos H, Heck, Donald, Leimgruber, Pierre P, Sheffet, Alice J, Howard, Virginia J, Chaturvedi, Seemant, Lal, Brajesh K, Voeks, Jenifer H, Hobson, Robert W, Castaldo, John |
| المصدر: | Department of Medicine |
| بيانات النشر: | LVHN Scholarly Works |
| سنة النشر: | 2016 |
| المجموعة: | Lehigh Valley Health Network: LVHN Scholarly Works |
| مصطلحات موضوعية: | Adult, Aged, 80 and over, Angioplasty, Carotid Stenosis, Endarterectomy, Carotid, Female, Follow-Up Studies, Humans, Life Expectancy, Male, Middle Aged, Myocardial Infarction, Risk, Stents, Stroke, Department of Medicine, Medicine and Health Sciences |
| الوصف: | BACKGROUND: In the Carotid Revascularization Endarterectomy versus Stenting Trial, we found no significant difference between the stenting group and the endarterectomy group with respect to the primary composite end point of stroke, myocardial infarction, or death during the periprocedural period or any subsequent ipsilateral stroke during 4 years of follow-up. We now extend the results to 10 years. METHODS: Among patients with carotid-artery stenosis who had been randomly assigned to stenting or endarterectomy, we evaluated outcomes every 6 months for up to 10 years at 117 centers. In addition to assessing the primary composite end point, we assessed the primary end point for the long-term extension study, which was ipsilateral stroke after the periprocedural period. RESULTS: Among 2502 patients, there was no significant difference in the rate of the primary composite end point between the stenting group (11.8%; 95% confidence interval [CI], 9.1 to 14.8) and the endarterectomy group (9.9%; 95% CI, 7.9 to 12.2) over 10 years of follow-up (hazard ratio, 1.10; 95% CI, 0.83 to 1.44). With respect to the primary long-term end point, postprocedural ipsilateral stroke over the 10-year follow-up occurred in 6.9% (95% CI, 4.4 to 9.7) of the patients in the stenting group and in 5.6% (95% CI, 3.7 to 7.6) of those in the endarterectomy group; the rates did not differ significantly between the groups (hazard ratio, 0.99; 95% CI, 0.64 to 1.52). No significant between-group differences with respect to either end point were detected when symptomatic patients and asymptomatic patients were analyzed separately. CONCLUSIONS: Over 10 years of follow-up, we did not find a significant difference between patients who underwent stenting and those who underwent endarterectomy with respect to the risk of periprocedural stroke, myocardial infarction, or death and subsequent ipsilateral stroke. The rate of postprocedural ipsilateral stroke also did not differ between groups. (Funded by the National Institutes of Health and Abbott ... |
| نوع الوثيقة: | text |
| اللغة: | unknown |
| العلاقة: | https://scholarlyworks.lvhn.org/medicine/6384Test; https://pubmed.ncbi.nlm.nih.gov/26890472Test/ |
| الإتاحة: | https://scholarlyworks.lvhn.org/medicine/6384Test https://pubmed.ncbi.nlm.nih.gov/26890472Test/ |
| رقم الانضمام: | edsbas.D4662407 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |