Periodontal regenerative medicine using mesenchymal stem cells and biomaterials: A systematic review of pre-clinical studies
| العنوان: | Periodontal regenerative medicine using mesenchymal stem cells and biomaterials: A systematic review of pre-clinical studies |
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| المؤلفون: | Pierre Weiss, Anne-Claire Marsden, Xavier Struillou, Mia Rakic, S. Portron, Christian Verner, Assem Soueidan, Zahi Badran |
| المساهمون: | Jehan, Frederic, Regenerative Medicine and Skeleton (RMeS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Département de parodontologie [UNIV Nantes] (Faculté de chirurgie dentaire), Université de Nantes (UN) |
| المصدر: | Dental Materials Journal Dental Materials Journal, Japanese Society for Dental Materials and Devices, 2019, Epub ahead of print. ⟨10.4012/dmj.2018-315⟩ |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Scaffold, Future studies, Materials science, Periodontal Ligament, 0206 medical engineering, Biocompatible Materials, 02 engineering and technology, Bioinformatics, Regenerative Medicine, Regenerative medicine, 03 medical and health sciences, 0302 clinical medicine, medicine, Periodontal fiber, Animals, Humans, Cementum, General Dentistry, Dental Cementum, [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, [SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology, Periodontal regeneration, [SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology, Regeneration (biology), Mesenchymal stem cell, Mesenchymal Stem Cells, 030206 dentistry, Biomaterial, 020601 biomedical engineering, medicine.anatomical_structure, Systematic review, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Ceramics and Composites, Pre-clinical study |
| الوصف: | International audience; The aim of the systematic review was to analyze the use of mesenchymal stem cells (MSC) and biomaterial for periodontal regeneration from preclinical animal models and human. Electronic databases were searched and additional hand-search in leading journals was performed. The research strategy was achieved according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The including criteria were as follows: MSC, biomaterial, in vivo studies, with histologic and radiologic analysis and written in English. The risk of bias was assessed for individual studies. A total of 50 articles were selected and investigated in the systematic review. These results indicate that MSC and scaffold provide beneficial effects on periodontal regeneration, with no adverse effects of such interventions. Future studies need to identify the suitable association of MSC and biomaterial and to characterize the type of new cementum and the organization of the periodontal ligament fiber regeneration. |
| وصف الملف: | application/pdf |
| تدمد: | 1881-1361 0287-4547 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0251360f8f1719756b4a1ef102935eTest https://pubmed.ncbi.nlm.nih.gov/31511473Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4f0251360f8f1719756b4a1ef102935e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18811361 02874547 |
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