Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis
| العنوان: | Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis |
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| المؤلفون: | Xin-Qun Wang, Joseph F. Polak, Stephen S. Rich, Ani Manichaikul, Jose D. Vargas, Jerome I. Rotter, Matthew J. Budoff, Wendy S. Post, David A. Bluemke |
| المصدر: | Vargas, JD; Manichaikul, A; Wang, X-Q; Rich, SS; Rotter, JI; Post, WS; et al.(2016). Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.. Data in Brief, 7, 229-242. doi: 10.1016/j.dib.2016.01.048. UCLA: Retrieved from: http://www.escholarship.org/uc/item/88d8k1m7Test Data in Brief, Vol 7, Iss, Pp 229-242 (2016) Data in Brief |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Aging, endocrine system diseases, Ethnic group, Single-nucleotide polymorphism, Genome-wide association study, Common genetic variant, Disease, Cardiovascular, lcsh:Computer applications to medicine. Medical informatics, Coronary artery calcium, Continuous variable, 03 medical and health sciences, Coronary artery calcium (CAC), Single nucleotide polymorphism (SNP), Internal medicine, Genetics, Medicine, Subdincal atherosclerosis, cardiovascular diseases, Carotid intima-media thickness, lcsh:Science (General), Heart Disease - Coronary Heart Disease, Subclinical infection, Data Article, Multidisciplinary, business.industry, Prevention, Human Genome, nutritional and metabolic diseases, Carotid intima-media thickness (CIMT), Atherosclerosis, Subclincal atherosclerosis, 3. Good health, Single nucleotide polymorphism, 030104 developmental biology, Heart Disease, Good Health and Well Being, Intima-media thickness, Subclinical atherosclerosis, Cardiology, cardiovascular system, lcsh:R858-859.7, population characteristics, business, lcsh:Q1-390 |
| الوصف: | Previously identified single nucleotide polymorphisms (SNPs) in genome wide association studies (GWAS) of cardiovascular disease (CVD) in participants of mostly European descent were tested for association with subclinical cardiovascular disease (sCVD), coronary artery calcium score (CAC) and carotid intima media thickness (CIMT) in the Multi-Ethnic Study of Atherosclerosis (MESA). The data in this data in brief article correspond to the article Common Genetic Variants and Subclinical Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis [1]. This article includes the demographic information of the participants analyzed in the article as well as graphical displays and data tables of the association of the selected SNPs with CAC and of the meta-analysis across ethnicities of the association of CIMT-c (common carotid), CIMT-I (internal carotid), CAC-d (CAC as dichotomous variable with CAC>0) and CAC-c (CAC as continuous variable, the log of the raw CAC score plus one) and CVD. The data tables corresponding to the 9p21 fine mapping experiment as well as the power calculations referenced in the article are also included. Keywords: Single nucleotide polymorphism (SNP), Common genetic variant, Subclincal atherosclerosis, Coronary artery calcium (CAC), Carotid intima-media thickness (CIMT) |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2352-3409 |
| DOI: | 10.1016/j.dib.2016.01.048 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a8b31ab7cce41c19335aae38e7bc24Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....40a8b31ab7cce41c19335aae38e7bc24 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23523409 |
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| DOI: | 10.1016/j.dib.2016.01.048 |