The Impact of Transcriptional Factors Znf1 and Sip4 on Xylose Alcoholic Fermentation in Recombinant Strains of Yeast Saccharomyces Cerevisiae
العنوان: | The Impact of Transcriptional Factors Znf1 and Sip4 on Xylose Alcoholic Fermentation in Recombinant Strains of Yeast Saccharomyces Cerevisiae |
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المؤلفون: | Kostyantyn V. Dmytruk, Andriy A. Sibirny, L. S. Dzanaeva, Justyna Ruchala |
المصدر: | Cytology and Genetics. 54:386-392 |
بيانات النشر: | Allerton Press, 2020. |
سنة النشر: | 2020 |
مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, Ethanol, biology, Saccharomyces cerevisiae, Cell Biology, Xylose, Ethanol fermentation, biology.organism_classification, 01 natural sciences, Agricultural and Biological Sciences (miscellaneous), Yeast, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Xylose metabolism, Biochemistry, Genetics, Ethanol fuel, Fermentation, 010606 plant biology & botany |
الوصف: | —In recent years, the demand for technical ethanol has increased due to its use in the transport sector. Xylose is the major five-carbon sugar obtained as a result of lignocellulose hydrolysis; however, the industrial producer of alcohol S. cerevisiae yeast ferments exclusively hexoses. Based on a recombinant strain capable of xylose metabolism, the derivatives with increased expression of the ZNF1 gene and deletion of the SIP4 gene encoding transcription factors were constructed. It was found that overexpression of the ZNF1 gene did not affect the fermentation of glucose or xylose. The deletion of the SIP4 gene did not affect the fermentation of glucose but resulted in a 29% decrease in ethanol production during xylose fermentation in comparison with the parental strain. |
تدمد: | 1934-9440 0095-4527 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::e57f9991647ed8385e7dddfa9c201987Test https://doi.org/10.3103/s0095452720050035Test |
حقوق: | CLOSED |
رقم الانضمام: | edsair.doi...........e57f9991647ed8385e7dddfa9c201987 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 19349440 00954527 |
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