Microparticles (Exosomes) and Atherosclerosis
| العنوان: | Microparticles (Exosomes) and Atherosclerosis |
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| المؤلفون: | Jing-Song Ou, Ya-Ting Chen, Hao-Xiang Yuan, Zhi-Jun Ou |
| المصدر: | Current Atherosclerosis Reports. 22 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Cell type, Cell Communication, 030204 cardiovascular system & hematology, Exosomes, Cell membrane, 03 medical and health sciences, 0302 clinical medicine, Cell-Derived Microparticles, In vivo, medicine, Animals, Humans, Secretion, 030212 general & internal medicine, Endothelial dysfunction, Multivesicular Body, Vascular Calcification, Inflammation, business.industry, Thrombosis, Atherosclerosis, medicine.disease, Microvesicles, medicine.anatomical_structure, Disease Progression, Cancer research, Endothelium, Vascular, Cardiology and Cardiovascular Medicine, business, Biomarkers, Calcification |
| الوصف: | This review summarizes the effects of microparticles and exosomes in the progression of atherosclerosis and the prospect for their diagnostic and therapeutic potentials. Microparticles and exosomes can induce endothelial dysfunction, vascular inflammation, coagulation, thrombosis, and calcification via their components of proteins and noncoding RNAs, which may promote the progression of atherosclerosis. The applications of microparticles and exosomes become the spotlight of clinical diagnosis and therapy. Microparticles and exosomes are members of extracellular vesicles, which are generated in various cell types by different mechanisms of cell membrane budding and multivesicular body secretion, respectively. They are important physiologic pathways of cell-to-cell communication in vivo and act as messengers accelerating or alleviating the process of atherosclerosis. Microparticles and exosomes may become diagnostic biomarkers and therapeutic approaches of atherosclerosis. |
| تدمد: | 1534-6242 1523-3804 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4bc59b09fe88b4eb839d4d963ab7ccTest https://doi.org/10.1007/s11883-020-00841-zTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ab4bc59b09fe88b4eb839d4d963ab7cc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15346242 15233804 |
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