Procalcitonin Value Is an Early Prognostic Factor Related to Mortality in Admission to Pediatric Intensive Care Unit
| العنوان: | Procalcitonin Value Is an Early Prognostic Factor Related to Mortality in Admission to Pediatric Intensive Care Unit |
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| المؤلفون: | Fatih Aygün |
| المصدر: | Critical Care Research and Practice Critical Care Research and Practice, Vol 2018 (2018) |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Inotrope, Mechanical ventilation, Pediatric intensive care unit, medicine.medical_specialty, Article Subject, business.industry, medicine.medical_treatment, lcsh:Medical emergencies. Critical care. Intensive care. First aid, lcsh:RC86-88.9, 030204 cardiovascular system & hematology, Critical Care and Intensive Care Medicine, Intensive care unit, Procalcitonin, law.invention, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, law, Blood Component Transfusion, Intensive care, Emergency medicine, medicine, Renal replacement therapy, business, Research Article |
| الوصف: | Introduction. Procalcitonin (PCT) and C-reactive protein (CRP) are already known predictive markers in serious bacterial infections, and it is emphasized that these biomarkers can be used as a marker of increased mortality in critically ill patients. Herein, we aimed to evaluate the initial serum PCT and CRP levels on the outcome of patients in pediatric intensive care units (PICUs) and find out if these biomarkers can be used to predict mortality. Materials and Methods. The relationship between the initial serum PCT and CRP levels and invasive mechanical ventilation (IMV) and noninvasive mechanical ventilation (NIV) support, inotropic drug need, acute renal kidney injury (AKI), continuous renal replacement therapy (CRRT), mortality, and hospitalization period was investigated retrospectively. Results. In total, 418 suitable patients (226 males and 192 females) were included in the study. Age distributions of patients ranged from 1 month to 17 years. There was a statistically significant relationship between PCT levels in the first biochemical analysis performed during admission and MV support, inotropic drug use, mortality, ARF, hospitalization in the intensive care unit, CRRT and blood component transfusion. There was a statistically significant relationship between CRP levels and MV support, NIV, inotropic drug use, mortality, AKI, hospitalization in the intensive care unit, CRRT, and blood component transfusion. Conclusion. We suggest that the initial PCT and CRP levels during admission can be used to predict the outcome of patients in PICU. |
| وصف الملف: | text/xhtml |
| تدمد: | 2090-1305 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb73ab1ce22a4474cfe7d356b9002d9dTest https://pubmed.ncbi.nlm.nih.gov/30675399Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....eb73ab1ce22a4474cfe7d356b9002d9d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20901305 |
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