Detailed Electromechanical Model of Ventricular Wedge

التفاصيل البيبلوغرافية
العنوان: Detailed Electromechanical Model of Ventricular Wedge
المؤلفون: Kursanov, A., Zverev, V., Katsnelson, L., Solovyova, O.
المصدر: Computing in Cardiology
بيانات النشر: IEEE Computer Society
سنة النشر: 2018
المجموعة: Ural Federal University (URFU): ELAR / Уральский федеральный университет: электронный архив УрФУ
مصطلحات موضوعية: CARDIOLOGY, COMPUTATIONAL GEOMETRY, WAVE PROPAGATION, COMPUTATIONAL MODEL, ELECTRO-MECHANICAL, ELECTROMECHANICAL MODELING, EXCITATION WAVES, MECHANICAL INTERACTIONS, MECHANO-ELECTRIC FEEDBACK, NONLINEAR PARTIAL DIFFERENTIAL EQUATIONS, NUMERICAL EXPERIMENTS, TISSUE
الوصف: We developed a three-dimensional computational model for describing electro-mechanical behavior of wedge-shaped preparation extracted from the left ventricular wall including excitation wave propagation, high-resolution geometry and fiber orientation. The cardiac tissue is simulated by an incompressible hyperplastic material. We used non-linear partial differential equations describing the deformation of the cardiac tissue, and a detailed 'Ekaterinburg-Oxford' (EO) cellular model of the electrical and mechanical activity of the cardiomyocytes in the tissue. Electro-mechanical coupling in the model accounts for mechano-electric feedbacks both in the cells and in the tissue. Numerical experiments with the model of the wedge preparation formed of initially identical cardiomyocytes revealed that electrical and mechanical interaction between the cells, as well as intracellular mechanoelectric feedbacks caused pronounced nonuniformity of their behavior. © 2018 Creative Commons Attribution. ; Russian Foundation for Basic Research, RFBR: 18-31-00416 ; Russian Academy of Sciences, RAS: АААА-А18- 118020590030-1 ; This work was carried out within the framework of the IIF UrB RAS themes (Nos. AAAA-A18-118020590031-8) and was supported by RFBR (18-31-00416), the Program of the Presidium RAS #27 (project АААА-А18- 118020590030-1) and Act 211 Government of the Russian Federation, contract № 02.A03.21.0006.
نوع الوثيقة: conference object
وصف الملف: application/pdf
اللغة: English
ردمك: 978-1-72810-958-9
1-72810-958-2
تدمد: 2325-8861
العلاقة: Detailed Electromechanical Model of Ventricular Wedge / A. Kursanov, V. Zverev, L. Katsnelson, O. Solovyova. — DOI 10.22489/CinC.2018.280 // Computing in Cardiology. — 2018. — Iss. 2018-September. — 8743913.; https://doi.org/10.22489/cinc.2018.280Test; b2c85d0a-b74b-43eb-8f8f-07550afa804f; http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85068765825Test; http://elar.urfu.ru/handle/10995/90052Test; 85068765825; 000482598700168
DOI: 10.22489/cinc.2018.280
الإتاحة: https://doi.org/10.22489/cinc.2018.280Test
https://doi.org/10.22489/CinC.2018.280Test
http://elar.urfu.ru/handle/10995/90052Test
http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85068765825Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.1F26613A
قاعدة البيانات: BASE
الوصف
ردمك:9781728109589
1728109582
تدمد:23258861
DOI:10.22489/cinc.2018.280