The seroprevalence of Bartonella spp. in the blood of patients with musculoskeletal complaints and blood donors, Poland: a pilot study
| العنوان: | The seroprevalence of Bartonella spp. in the blood of patients with musculoskeletal complaints and blood donors, Poland: a pilot study |
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| المؤلفون: | Magdalena Konieczka, Monika Łysakowska, Sylwia Moskwa, Dorota Pastuszak-Lewandoska, Joanna Makowska, Malgorzata Szybka, Olga Brzezińska, Janina Grzegorczyk, Małgorzata Brauncajs |
| المصدر: | Clinical Rheumatology. 38:2691-2698 |
| بيانات النشر: | Springer Science and Business Media LLC, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, Bartonella, medicine.medical_specialty, Bacteremia, Blood Donors, Pilot Projects, Tick, Asymptomatic, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Risk Factors, Seroepidemiologic Studies, Bartonella Infections, Internal medicine, Epidemiology, medicine, Humans, Seroprevalence, Bites and Stings, Musculoskeletal Diseases, 030212 general & internal medicine, Aged, 030203 arthritis & rheumatology, biology, business.industry, Insect Bites and Stings, Cat-scratch disease, General Medicine, Middle Aged, bacterial infections and mycoses, medicine.disease, biology.organism_classification, Antibodies, Bacterial, Trench fever, Immunoglobulin M, Immunoglobulin G, Female, Poland, medicine.symptom, business |
| الوصف: | Bartonella spp. can cause a variety of diseases, such as lymphadenopathies, cat scratch disease, and trench fever, but can also give rise to many non-specific symptoms. No data exists regarding the prevalence of Bartonella spp. in patients with musculoskeletal complaints, nor among blood donors in Poland. The presence of anti-Bartonella IgM and IgG in the serum of blood donors (n = 65) (Lodz, Poland) and in the patients of the Department of Rheumatology Clinic (n = 40) suffering from musculoskeletal symptoms was tested by immunofluorescence. Blood samples were cultured on enriched media. Epidemiological questionnaires were used to identify key potential risk factors, such as sex, age, contact with companion animals, and bites from insects or animals. Altogether, 27 of the 105 tested subjects were seropositive for Bartonella henselae IgG (23%) and three for Bartonella quintana IgG (2.85%); IgMs against B. henselae were found in three individuals (2.85%), and IgMs against B. quintana were found in one (1.54%). No statistically significant difference was found between the prevalence of B. henselae in the blood of donors or patients and the presence of unexplained musculoskeletal complaints (23% vs 30%). Individuals who had kept or been scratched by cats were not more likely to be B. henselae seropositive (p > 0.01). Tick bites were more commonly reported in patients, but insignificantly (p > 0.01). This is the first report of a high seroprevalence of anti-Bartonella IgG in patients with musculoskeletal symptoms and in blood donors in Poland. The obtained results indicate that such seroprevalence may have a possible significance in the development of musculoskeletal symptoms, although it should be confirmed on a larger group of patients. Asymptomatic bacteremia might occur and pose a threat to recipients of blood from infected donors. Hence, there is a need for more detailed research, including molecular biology methods, to clarify the potential risk of Bartonella spp. being spread to immunocompromised individuals. • This is the first study presenting high seroprevalence of Bartonella spp. in Poland. • IgG and IgM antibodies against B. quintana were found in blood samples of blood donors. |
| تدمد: | 1434-9949 0770-3198 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40935c032c9fa7d69f2a6f93567bfb58Test https://doi.org/10.1007/s10067-019-04591-5Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....40935c032c9fa7d69f2a6f93567bfb58 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14349949 07703198 |
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