There were no significant differences in terms of age, sex and levels of 25 OHD. Serum Ca and phosphate levels were normal in 96% and 88% of patients respectively. Patients with higher levels of body fat have lower serum 25 OHD (r = 0.50, p = 0.009), with no differences between men and women. Following weight loss, the prevalence of hypovitaminosis was reduced to 46% and the rate of hyperparathyroidism fell by 78%. At the same time, a significant correlation between this hormone and serum 25 OHD; r = 0.554, P= 0.01 was found. The loss of fat mass appears to be associated with the reduction of hypovitaminosis, as we observe an inverse correlation between increased serum levels of 25 OHD; r = 0.35, p = 0.001 and adipose tissue. Conclusion: hypovitaminosis D is highly prevalent in MO patients. Serum levels improve following the loss of fat mass, which suggests higher plasma availability.