التفاصيل البيبلوغرافية
| العنوان: |
The applicability of the digit wrinkle scan to quantify sympathetic nerve function |
| المؤلفون: |
Maurice Sopacua, Carla M.L. Gorissen-Brouwers, Bianca T.A. de Greef, Isis B.T. Joosten, Catharina G. Faber, Ingemar S.J. Merkies, Janneke G.J. Hoeijmakers |
| المصدر: |
Clinical Neurophysiology Practice, Vol 7, Iss , Pp 115-119 (2022) |
| بيانات النشر: |
Elsevier, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| مصطلحات موضوعية: |
5-point scale, Digit wrinkle scan, Small fiber neuropathy, Autonomic function, Digit vasoconstriction, Inter-observer reliability, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: |
Objective: Stimulated skin wrinkling test (SSW) has been launched as a non-invasive diagnostic procedure. However, no normative age dependent values have been reported that can be applied in clinical practice. The objectives of the study were to (1) collect age-dependent normative values according to the 5-point scale assessment for the SSW, to (2) determine reliability scores for the obtained norm values, and to (3) introduce a new digital method for SSW assessment, the Digit Wrinkle Scan© (DWS©) for detection of wrinkles in a more quantitative manner. Methods: Firstly, 82 healthy participants were included, divided in 5 age groups. The participants underwent SSW using lidocaine and prilocaine topical cream. Secondly, 35 healthy participants were included to test whether the DWS© could be a novel manner to assess the grade of wrinkling quantitatively. We determined the inter-observer reliability of both methods. Also, the intra-observer reliability was calculated for the DWS©. Results: We found a decrease in normative values over age. The inter-observer reliability of assessment by the 5-point scale method was moderate after SSW (Cohen’s k: 0.53). Results of the DWS© indicate that total wrinkle length per mm2 showed moderate to good agreement for the 4th and 5th digits after SSW, and a low agreement for the other digits. Conclusions: Age-dependent normative values were obtained according to the 5-point scale, but its clinical application is doubtful since we found a moderate inter-observer reliability. We introduced the DWS© as a possible new method in order to quantify the grade of wrinkling. Significance: We found unsatisfactory reliability scores, which hampers its usefulness for clinical practice. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2467-981X |
| العلاقة: |
http://www.sciencedirect.com/science/article/pii/S2467981X22000166Test; https://doaj.org/toc/2467-981XTest |
| DOI: |
10.1016/j.cnp.2022.03.005 |
| الوصول الحر: |
https://doaj.org/article/19bc50ebc46544029cbcae873b0fddefTest |
| رقم الانضمام: |
edsdoj.19bc50ebc46544029cbcae873b0fddef |
| قاعدة البيانات: |
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