Correlation between myocardial enzyme serum levels and markers of inflammation with severity of coronary artery disease and Gensini score: A hospital-based, prospective study in Greek patients
| العنوان: | Correlation between myocardial enzyme serum levels and markers of inflammation with severity of coronary artery disease and Gensini score: A hospital-based, prospective study in Greek patients |
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| المؤلفون: | Stylianos Rokas, Efstathios Manios, Vasileios Peppes, Eleni Koroboki, George Rammos, Nikolaos Zakopoulos |
| المصدر: | Clinical Interventions in Aging, Vol Volume 3, Pp 699-710 (2008) Clinical Interventions in Aging Scopus-Elsevier |
| بيانات النشر: | Dove Medical Press, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Myocardial Infarction, Coronary Artery Disease, Severity of Illness Index, Coronary artery disease, chemistry.chemical_compound, Sex Factors, Risk Factors, Internal medicine, Lactate dehydrogenase, Severity of illness, medicine, Humans, Myocardial infarction, Prospective Studies, Prospective cohort study, Original Research, medicine.diagnostic_test, biology, Greece, business.industry, Myocardium, Case-control study, RC952-954.6, General Medicine, Middle Aged, medicine.disease, chemistry, inflammation, Geriatrics, Clinical Interventions in Aging, Erythrocyte sedimentation rate, Case-Control Studies, Cardiology, biology.protein, Myocardial enzymes, Creatine kinase, Female, Geriatrics and Gerontology, Inflammation Mediators, coronary angiography, business |
| الوصف: | Vasileios Peppes, George Rammos, Efstathios Manios, Eleni Koroboki, Stylianos Rokas, Nikolaos ZakopoulosDepartment of Clinical Therapeutics, Alexandra Hospital, University of Athens School of Medicine, Athens, GreeceBackground: Our objective was to associate serum levels of myocardial enzymes and inflammatory biomarkers with severity of coronary artery disease (CAD).Patients and methods: 123 patients participated in our study, including 65 cases of acute myocardial infarction (MI), 27 cases of newly diagnosed CAD – without MI – and 31 controls. In all subjects, myocardial serum enzyme levels (creatine phosphokinase, aspartate aminotransferase, lactate dehydrogenase) and inflammatory indices (C-reactive protein, fibrinogen, white blood cells, and erythrocyte sedimentation rate) were measured. Patients were all submitted to coronary angiography and CAD severity was evaluated by Gensini score.Results: Significant differences concerning enzyme serum levels and inflammatory indices were found to exist between the three study groups, being highest among patients with acute MI (p< 0.001). A significant association was demonstrated between Gensini score and serum enzyme levels as well as inflammatory biomarkers.Conclusions: Our findings suggest that serum levels of myocardial enzymes and inflammatory indices correlate with CAD severity in Greek patients.Keywords: myocardial enzymes, inflammation, coronary angiography, coronary artery disease |
| وصف الملف: | text/html |
| اللغة: | English |
| تدمد: | 1178-1998 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a725e4ef689578f06c751a3444c2bbeTest https://www.dovepress.com/correlation-between-myocardial-enzyme-serum-levels-and-markers-of-infl-peer-reviewed-article-CIATest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0a725e4ef689578f06c751a3444c2bbe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11781998 |
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