التفاصيل البيبلوغرافية
| العنوان: |
Nosocomial Acquisition of Multiresistant Acinetobacter baumannii: Risk Factors and Prognosis. |
| المؤلفون: |
Lortholary, Olivier, Fagon, Jean-Yves, Hoi, Annie Buu, Slama, Michel A., Pierre, Josiane, Giral, Philippe, Rosenzweig, Rachel, Gutmann, Laurent, Safar, Michel, Acar, Jacques |
| المصدر: |
Clinical Infectious Diseases; 1995, Vol. 20 Issue 4, p790-796, 7p |
| مستخلص: |
To identify risk factors for and prognostic indicators of the nosocomial acquisition of multiresistant Acinetobacter baumannii in an intensive care unit, we prospectively studied 40 patients: 13 who were infected with this organism and 27 who were colonized. Isolates were identified by pulsed-field gel electrophoresis; the infected/colonized patients were compared with 348 noninfected, noncolonized patients by logistic regression analysis and with matched historical controls in a cohort study. The severity of illness (evaluated by the APACHE II score; P < .05) and previous infection (P < .001) were retained as independent risk factors for acquiring A, baumannii. Logistic regression analysis selected a high APACHE II score (P < .01) and the acquisition of A. baumannii (P < .01) as factors independently associated with death. The acquisition of A. baumannii was associated not only with high mortality but also with a length of stay on the intensive care unit in excess of that due to the underlying disease alone; specifically, the attributable mortality was 25%, with a risk ratio for death of 2.0 (95% confidence interval, 1.11–3.62), and the duration of stay for infected/colonized patients was 10.3 days longer than that for controls (P < .001). [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |
