التفاصيل البيبلوغرافية
| العنوان: |
Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio. |
| المؤلفون: |
Bradley, John, Soumaré, Harouna M, Mahamar, Almahamoudou, Diawara, Halimatou, Roh, Michelle, Delves, Michael, Drakeley, Chris, Churcher, Thomas S, Dicko, Alassane, Gosling, Roly, Bousema, Teun |
| المصدر: |
Clinical Infectious Diseases; 10/15/2019, Vol. 69 Issue 8, p1436-1439, 4p |
| مصطلحات موضوعية: |
DRUG therapy for malaria, MALARIA transmission, GERM cells, METHYLENE blue, MOSQUITOES, PRIMAQUINE, PROTOZOA, SEX distribution, STERILIZATION (Disinfection), PHARMACODYNAMICS |
| مستخلص: |
Gametocyte density and sex ratio can predict the proportion of mosquitoes that will become infected after feeding on blood of patients receiving nongametocytocidal drugs. Because primaquine and methylene blue sterilize gametocytes before affecting their density and sex ratio, mosquito feeding experiments are required to demonstrate their early transmission-blocking effects. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
