Temporal Dynamics of Anti–Type 1 Interferon Autoantibodies in Patients With Coronavirus Disease 2019
العنوان: | Temporal Dynamics of Anti–Type 1 Interferon Autoantibodies in Patients With Coronavirus Disease 2019 |
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المؤلفون: | Elana R Shaw, Lindsey B Rosen, Aristine Cheng, Kerry Dobbs, Ottavia M Delmonte, Elise M N Ferré, Monica M Schmitt, Luisa Imberti, Virginia Quaresima, Michail S Lionakis, Luigi D Notarangelo, Steven M Holland, Helen C Su |
المصدر: | Clinical Infectious Diseases. 75:e1192-e1194 |
بيانات النشر: | Oxford University Press (OUP), 2021. |
سنة النشر: | 2021 |
مصطلحات موضوعية: | Microbiology (medical), Infectious Diseases |
الوصف: | Binding levels and neutralization activity of anti–type 1 interferon autoantibodies peaked during acute coronavirus disease 2019 and markedly decreased thereafter. Most patients maintained some ability to neutralize type 1 interferon into convalescence despite lower levels of binding immunoglobulin G. Identifying these autoantibodies in healthy individuals before the development of critical viral disease may be challenging. |
تدمد: | 1537-6591 1058-4838 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::8a74536c40a2eadca2a127e12f3f329fTest https://doi.org/10.1093/cid/ciab1002Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi...........8a74536c40a2eadca2a127e12f3f329f |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15376591 10584838 |
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