Time to dp/dtmax, a useful index for evaluation of contractility in the catheterization laboratory
| العنوان: | Time to dp/dtmax, a useful index for evaluation of contractility in the catheterization laboratory |
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| المؤلفون: | E. Scott Monrad, Otto M. Hess, David Adler, F.A.C.C. Hans P. Krayenbuehl M.D., F.A.C.C Edmund H. Sonnenblick Md. |
| المصدر: | Clinical Cardiology. 19:397-403 |
| بيانات النشر: | Wiley, 1996. |
| سنة النشر: | 1996 |
| مصطلحات موضوعية: | Cardiac Catheterization, medicine.medical_specialty, Myocardial Failure, Contraction (grammar), medicine.medical_treatment, Ventricular Function, Left, Contractility, Heart Rate, Internal medicine, Dp dtmax, Ventricular Pressure, medicine, Humans, Isovolumetric contraction, Cardiac catheterization, Heart Failure, business.industry, General Medicine, medicine.disease, Myocardial Contraction, Heart failure, Ventricular pressure, Cardiology, Cardiology and Cardiovascular Medicine, business, Mathematics |
| الوصف: | Hypothesis : The time from onset of contraction to dP/dt max , t d , is suggested as an index of contractility in the catheterization laboratory. Methods : We studied 22 normal patients and 18 patients with myocardial failure in the catheterization laboratory. The two groups were completely separated on the td-heart rate (HR) plane. In the normal patients, HR = 73 ± 19 beats/min, t d = 73 ± 11 ms, and an inverse linear relation t d = 109-0.49 x HR (p < 0.001) exist. In the patients with myocardial failure, despite significantly higher HR than in normal patients (HR = 93 ± 14 beats/min) (p < 0.001), t d paradoxically increased (t d = 89 ± 11 ms, p < 0.0001). Conclusions : These findings support a mathematical analysis of the left ventricular pressure (LVP) during isovolumic contraction in the time domain which shows that t d and (dP/dt)/P reflect the time-dependent aspects of contraction and, hence, decrease with increasing contractility. This study shows that t d , at any given HR, is a reliable index of contractility. Thus, a ready-to-use t d -HR plot containing a well-based separation line can provide a reliable and simple method for determining contractility in the catheterization laboratory by examining whether a patient's t d value at any HR is below (normal) or above (impaired contractility) the separation line. |
| تدمد: | 1932-8737 0160-9289 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd14c6698f0bf399299a6976d9daa29Test https://doi.org/10.1002/clc.4960190513Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2fd14c6698f0bf399299a6976d9daa29 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19328737 01609289 |
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