المؤلفون: Qing Zhou, Lin Wu, Pei Hu, Tongtong An, Jianying Zhou, Li Zhang, Xiao-Qing Liu, Feng Luo, Xin Zheng, Ying Cheng, Nong Yang, Junling Li, Jifeng Feng, Baohui Han, Yong Song, Kai Wang, Jian Fang, Hong Zhao, Yongqian Shu, Xiao-Yan Lin, Zhihong Chen, Bin Gan, Wan-Hong Xu, Wei Tang, Xiaoying Zhang, Jin-Ji Yang, Xiao Xu, Yi-Long Wu

المصدر: Clinical Cancer Research. 28:1127-1135

مصطلحات موضوعية: Adult, Cancer Research, medicine.medical_specialty, Lung Neoplasms, EGFR T790M, Gastroenterology, Pharmacokinetics, Carcinoma, Non-Small-Cell Lung, Internal medicine, Humans, Point Mutation, Medicine, Clinical efficacy, Lung cancer, Protein Kinase Inhibitors, EGFR inhibitors, business.industry, medicine.disease, Third generation, ErbB Receptors, Pyrimidines, Oncology, Mutation, Non small cell, business, Egfr tyrosine kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef172334327b78f078f2ebc1a309df2Test
https://doi.org/10.1158/1078-0432.ccr-21-2595Test

المؤلفون: Juliet Williams, Jeffrey A. Engelman, Guizhi Yang, Matthew J. Meyer, Huai Xiang Hao, William D. Hastings, Chen Liu, Tinya Abrams, Silvia Goldoni, Hui Gao, Giordano Caponigro, Peter S. Hammerman, Hongyun Wang, Colleen Kowal, Scott Delach, Alice Loo, Hengyu Lu, Susan Moody, Matthew J. LaMarche, Ye Wang, Karrie Wong, Morvarid Mohseni, Xiamei Zhang

المصدر: Clinical Cancer Research. 27:342-354

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Programmed Cell Death 1 Receptor, Allosteric regulation, Protein Tyrosine Phosphatase, Non-Receptor Type 11, medicine.disease_cause, Receptor tyrosine kinase, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, medicine, Animals, Humans, Immune Checkpoint Inhibitors, Protein Kinase Inhibitors, EGFR inhibitors, Tumor microenvironment, biology, Chemistry, Cyclin-Dependent Kinase 4, Cancer, Drug Synergism, Cyclin-Dependent Kinase 6, medicine.disease, Xenograft Model Antitumor Assays, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, biology.protein, Cancer research, Female, KRAS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3c3f6b2f214726db8bd9a82f04ec4Test
https://doi.org/10.1158/1078-0432.ccr-20-2718Test

المؤلفون: Sung Sook Lee, Young Sung Lee, Min Hee Hong, Mi Ran Yun, Kyoung Ho Pyo, Byoung Chul Cho, Koh Jong Sung, Hye Ryun Kim, Han Na Kang, So-Young Kim, Ho Juhn Song, Dong-Kyun Kim, Se Woong Oh, Soongyu Choi, Chae Won Park, Jiyeon Yun, Seok Young Kim

المصدر: Clinical Cancer Research. 25:2575-2587

مصطلحات موضوعية: Adult, Male, Models, Molecular, Cancer Research, Lung Neoplasms, Cell Survival, Mice, Structure-Activity Relationship, T790M, In vivo, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Animals, Humans, Osimertinib, Lung cancer, Protein Kinase Inhibitors, EGFR inhibitors, Acrylamides, Aniline Compounds, Brain Neoplasms, Kinase, business.industry, medicine.disease, Xenograft Model Antitumor Assays, ErbB Receptors, Disease Models, Animal, Treatment Outcome, Oncology, Blood-Brain Barrier, Drug Resistance, Neoplasm, Apoptosis, Mutation, Cancer research, business, Brain metastasis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2e1b9c5e8c61e1e0aee66daa030268Test
https://doi.org/10.1158/1078-0432.ccr-18-2906Test

المؤلفون: Crystal Turner, Sosipatros A. Boikos, Yoshiko Murakami, Bin Hu, Jungoh Ham, Colin M. Coon, Neha U. Patel, Andrew J. Souers, Anthony C. Faber, Yasushi Yatabe, Yasuyuki Hosono, Timothy L. Lochmann, Joel D. Leverson, Brad Windle, Aaron N. Hata, Jennifer E. Koblinski, Krista M. Powell, Hiromichi Ebi, Hisashi Harada, Sheeba Jacob, Kyung-A Song, Yuko Oya

المصدر: Clinical Cancer Research. 24:5658-5672

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Mutation, business.industry, Kinase, Cancer, medicine.disease, medicine.disease_cause, 03 medical and health sciences, T790M, 030104 developmental biology, Oncology, Downregulation and upregulation, In vivo, Cancer research, Medicine, business, Lung cancer, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e96ac33b7d3ceceab16675a0e4a26b37Test
https://doi.org/10.1158/1078-0432.ccr-18-0304Test

المؤلفون: Jungoh Ham, Anthony C. Faber, Aaron N. Hata, Maria Gomez-Caraballo, Haichuan Hu, Elizabeth L. Lockerman, Brad Windle, Shawn Gillepsie, Daniel A. R. Heisey, Sinem Esra Sahingur, Mark A. Hicks, Kyung-A Song, Shirley M. Taylor, Hillary E. Mulvey, Timothy L. Lochmann, Hiromichi Ebi, Lecia V. Sequist, Konstantinos V. Floros, Mark T. Hughes, Hidenori Kitai, Hannah L. Archibald, Angel R. Garcia, Yotam Drier, Mikhail G. Dozmorov, Tara J. Nulton, Neha U. Patel, Matthew J. Niederst, Zofia Piotrowska, Bradley E. Bernstein, Jeffrey A. Engelman

المصدر: Clinical Cancer Research. 24:197-208

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Epithelial-Mesenchymal Transition, Lung Neoplasms, Apoptosis, Biology, Bioinformatics, Article, Mice, 03 medical and health sciences, medicine, Animals, Humans, Molecular Targeted Therapy, Epithelial–mesenchymal transition, RNA, Small Interfering, Promoter Regions, Genetic, Lung cancer, Protein Kinase Inhibitors, Transcription factor, EGFR inhibitors, Regulation of gene expression, Sulfonamides, Aniline Compounds, Bcl-2-Like Protein 11, Cell Cycle, Mesenchymal stem cell, medicine.disease, ErbB Receptors, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Editorial, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, Mutation, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68885df70454ff0b5a951a10f3b18bd6Test
https://doi.org/10.1158/1078-0432.ccr-17-1577Test

المؤلفون: Hillary E. Mulvey, Jeffrey A. Engelman, Lecia V. Sequist, Haichuan Hu, Elizabeth L. Lockerman, Angel R. Garcia, Matthew J. Niederst, Zofia Piotrowska

المصدر: Clinical Cancer Research. 21:3924-3933

مصطلحات موضوعية: Cancer Research, Mutation, Cancer, Context (language use), Drug resistance, Biology, Pharmacology, medicine.disease_cause, medicine.disease, respiratory tract diseases, T790M, Oncology, medicine, Cancer research, Rociletinib, Erlotinib, EGFR inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::707d7b2a854af570165ea3fa73b0181bTest
https://doi.org/10.1158/1078-0432.ccr-15-0560Test

المؤلفون: Jungoh Ham, Kyung-A Song, Aaron N. Hata, Hiromichi Ebi, Hisashi Harada, Brad Windle, Joel D. Leverson, Neha U. Patel, Andrew J. Souers, Anthony C. Faber, Timothy L. Lochmann

المصدر: Clinical Cancer Research. 24:B31-B31

مصطلحات موضوعية: Cancer Research, Mutation, business.industry, Kinase, Cancer, medicine.disease_cause, medicine.disease, respiratory tract diseases, T790M, Gefitinib, Oncology, Cancer research, medicine, business, Lung cancer, PI3K/AKT/mTOR pathway, medicine.drug, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5aa02c20b295650d39671cfab12d0996Test
https://doi.org/10.1158/1557-3265.aacriaslc18-b31Test

المؤلفون: Ezra E.W. Cohen, Lucy F. Chen, Jennifer R. Grandis

المصدر: Clinical Cancer Research. 16:2489-2495

مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Angiogenesis, medicine.disease_cause, Models, Biological, Article, Metastasis, Growth factor receptor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Epidermal growth factor receptor, EGFR inhibitors, Mutation, biology, business.industry, Head and neck cancer, Cancer, medicine.disease, ErbB Receptors, Oncology, Drug Resistance, Neoplasm, Head and Neck Neoplasms, Cancer research, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a492b8de54fbaa478a639286877ed9Test
https://doi.org/10.1158/1078-0432.ccr-09-2318Test

المؤلفون: John V. Heymach, Eugene Lifshits, George N. Naumov, Tina Cascone, Daniel G. Tenen, Bruce E. Johnson, Lars A. Akslen, Jeffrey A. Engelman, Monique B. Nilsson, Hua Kang Wu, Oddbjørn Straume, Pasi A. Jänne, Beow Y. Yeap, Balazs Halmos, Xi M. Tang, Alexandra Briggs, Judah Folkman, Lauren Averett Byers, Li Xu, Susumu Kobayashi

المصدر: Clinical Cancer Research. 15:3484-3494

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Cancer Research, Lung Neoplasms, Time Factors, Blotting, Western, Mice, Nude, Biology, Antibodies, Monoclonal, Humanized, Transfection, medicine.disease_cause, Vandetanib, Article, Erlotinib Hydrochloride, Mice, Gefitinib, Piperidines, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Epidermal growth factor receptor, neoplasms, Cell Proliferation, EGFR inhibitors, Reverse Transcriptase Polymerase Chain Reaction, Antibodies, Monoclonal, Xenograft Model Antitumor Assays, Tumor Burden, respiratory tract diseases, Bevacizumab, ErbB Receptors, Receptors, Vascular Endothelial Growth Factor, Oncology, Drug Resistance, Neoplasm, Mutation, NIH 3T3 Cells, Quinazolines, Cancer research, biology.protein, KRAS, Erlotinib, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a2ea89b5df0539a0e523946c8d144bTest
https://doi.org/10.1158/1078-0432.ccr-08-2904Test

المؤلفون: Sabine Tejpar, Wendy De Roock, Diether Lambrechts, Bart Claes, Eric Van Cutsem, Hans Prenen, Bart Jacobs, Jef De Schutter, Bart Biesmans

المصدر: Clinical cancer research

مصطلحات موضوعية: Male, Cancer Research, Colorectal cancer, Cetuximab, medicine.disease_cause, Cohort Studies, Phosphatidylinositol 3-Kinases, Antineoplastic Combined Chemotherapy Protocols, Epidermal growth factor receptor, EGFR inhibitors, Aged, 80 and over, biology, Antibodies, Monoclonal, Middle Aged, Prognosis, ErbB Receptors, Survival Rate, Treatment Outcome, Oncology, KRAS, Colorectal Neoplasms, medicine.drug, Adult, Maximum Tolerated Dose, Class I Phosphatidylinositol 3-Kinases, Adenocarcinoma, Antibodies, Monoclonal, Humanized, Irinotecan, Proto-Oncogene Proteins p21(ras), Growth factor receptor, Proto-Oncogene Proteins, medicine, Humans, PTEN, neoplasms, Aged, Neoplasm Staging, business.industry, Cancer, medicine.disease, digestive system diseases, Drug Resistance, Neoplasm, Mutation, Immunology, ras Proteins, Cancer research, biology.protein, Camptothecin, Human medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e69bba82c5d7cfd2f362a830383a552Test
https://doi.org/10.1158/1078-0432.ccr-08-2961Test