نتائج البحث

1

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Triple Negative Breast Neoplasms, Disease, CD8-Positive T-Lymphocytes, Article, B7-H1 Antigen, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Breast cancer, Albumins, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, medicine, Humans, Aged, Chemotherapy, business.industry, Immunotherapy, Middle Aged, Gene signature, Prognosis, medicine.disease, Neoadjuvant Therapy, Progression-Free Survival, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Cytokine secretion, Neoplasm Recurrence, Local, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb791e74b1e7256046bab4264aacd2Test
https://doi.org/10.1158/1078-0432.ccr-19-3685Test

2

Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study

المؤلفون: Burak Gumuscu, Kevin J. Harrington, Hoi-Shen Radcliffe, Lillian L. Siu, Wendy Snyder, Danny Rischin, Beatriz Castelo Fernandez, Ezra E.W. Cohen, Jason Chesney, Anthony Kong, Jonathan D. Cheng, Nicolas Mach

المصدر: Clinical Cancer Research, Vol. 26, No 19 (2020) pp. 5153-5161

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Herpesvirus 1, Human, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Multicenter trial, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Neoplasm Metastasis, Adverse effect, Aged, ddc:616, Oncolytic Virotherapy, Biological Products, Chemotherapy, Squamous Cell Carcinoma of Head and Neck, business.industry, Middle Aged, medicine.disease, Combined Modality Therapy, Head and neck squamous-cell carcinoma, Progression-Free Survival, 030220 oncology & carcinogenesis, Female, Immunotherapy, Neoplasm Recurrence, Local, Talimogene laherparepvec, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e68d707fa9e943a6b37439bfbf54a5aTest
https://doi.org/10.1158/1078-0432.ccr-20-1170Test

3

Nivolumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use

المؤلفون: Jeffery S. Russell, Shanmugasundaram Ramkumar, Everett E. Vokes, Robert L. Ferris, Makoto Tahara, Maura L. Gillison, Lisa Licitra, Mark Lynch, Robert I. Haddad, Joël Guigay, Caroline Even, Nabil F. Saba, Kevin J. Harrington, Fernando Concha-Benavente, Jérôme Fayette, Li Li, Peter Brossart, George R. Blumenschein, A. Dimitrios Colevas

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Cetuximab, Article, law.invention, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, Clinical endpoint, medicine, Humans, Neoplasm Metastasis, Survival rate, Aged, Aged, 80 and over, Chemotherapy, Squamous Cell Carcinoma of Head and Neck, business.industry, Immunotherapy, Middle Aged, ErbB Receptors, Survival Rate, Clinical trial, Nivolumab, 030104 developmental biology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Neoplasm Recurrence, Local, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a754089cc56f4bc972d5ecdf0accbd84Test
https://doi.org/10.1158/1078-0432.ccr-18-3944Test

4

Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors

المؤلفون: Elizabeth Blackwood, Jennifer O. Lauchle, Rui Zhu, Yuan Chen, Jean-Charles Soria, Srikumar Sahasranaman, Xuyang Lu, Jennifer L. Schutzman, Patricia LoRusso, Elaine Murray, Franklin Peale, Sami Mahrus, Sophie Postel-Vinay, Jeffrey R. Infante, Xiao Ding, Todd M. Bauer, Antoine Hollebecque, Marie Evangelista

المصدر: Clinical Cancer Research. 23:2423-2432

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, Nausea, medicine.medical_treatment, Triple Negative Breast Neoplasms, Pharmacology, Neutropenia, Deoxycytidine, Gastroenterology, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Piperidines, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Melanoma, Aged, Chemotherapy, Dose-Response Relationship, Drug, business.industry, Cancer, Middle Aged, medicine.disease, Gemcitabine, 030104 developmental biology, Oncology, Tolerability, Bone marrow suppression, 030220 oncology & carcinogenesis, Checkpoint Kinase 1, Vomiting, Female, medicine.symptom, business, Heterocyclic Compounds, 3-Ring, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c5bc855dc1b1a96d7edd9072a8b2c0Test
https://doi.org/10.1158/1078-0432.ccr-16-1782Test

5

mdr-1 Single Nucleotide Polymorphisms in Ovarian Cancer Tissue: G2677T/A Correlates with Response to Paclitaxel Chemotherapy

المؤلفون: Peter Söderkvist, György Horvath, Henrik Gréen, Per Rosenberg, Carsten Peterson

المصدر: Clinical Cancer Research. 12:854-859

مصطلحات موضوعية: Adult, Medicin och hälsovetenskap, Cancer Research, Genotype, Paclitaxel, medicine.medical_treatment, DNA Mutational Analysis, Single-nucleotide polymorphism, Biology, Medical and Health Sciences, Polymorphism, Single Nucleotide, Carboplatin, chemistry.chemical_compound, Predictive Value of Tests, Recurrence, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Gene, Mdr 1 gene, Aged, Ovarian Neoplasms, Chemotherapy, Reverse Transcriptase Polymerase Chain Reaction, Exons, Middle Aged, medicine.disease, Ovary cancer, Multiple drug resistance, Treatment Outcome, Oncology, chemistry, Immunology, Disease Progression, Cancer research, Female, Ovarian cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f44f4c2574aa786e180b21461c1da3Test
https://doi.org/10.1158/1078-0432.ccr-05-0950Test

6

Association of Breast Cancer Stem Cells Identified by Aldehyde Dehydrogenase 1 Expression with Resistance to Sequential Paclitaxel and Epirubicin-Based Chemotherapy for Breast Cancers

المؤلفون: Yoshio Tanji, Yasuhiro Tamaki, Tetsuya Taguchi, Seung Jin Kim, Kenzo Shimazu, Shinzaburo Noguchi, Tomonori Tanei, Koji Morimoto

المصدر: Clinical Cancer Research. 15:4234-4241

مصطلحات موضوعية: Adult, Oncology, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Antigens, Differentiation, Myelomonocytic, CA 15-3, Breast Neoplasms, Aldehyde Dehydrogenase 1 Family, Breast cancer, Antigens, CD, Antigens, Neoplasm, Cancer stem cell, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, skin and connective tissue diseases, Aged, Epirubicin, Chemotherapy, Antibiotics, Antineoplastic, Predictive marker, biology, business.industry, CD44, CD24 Antigen, Retinal Dehydrogenase, Aldehyde Dehydrogenase, Middle Aged, medicine.disease, Antineoplastic Agents, Phytogenic, Neoadjuvant Therapy, DNA-Binding Proteins, Isoenzymes, DNA Topoisomerases, Type II, Hyaluronan Receptors, Ki-67 Antigen, Drug Resistance, Neoplasm, Neoplastic Stem Cells, biology.protein, Female, Stem cell, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ade3d412db06cef1cb0fd38748cd7abTest
https://doi.org/10.1158/1078-0432.ccr-08-1479Test

7

A Phase I Study of the P-Glycoprotein Antagonist Tariquidar in Combination with Vinorelbine

المؤلفون: Rob Robey, Richard H. Wilson, Susan E. Bates, Andrew J. Dwyer, Clara C. Chen, Ann Rutt, Frank M. Balis, Jame Abraham, Tito Fojo, Barry R. Goldspiel, Olaf Van Tellingen, Maureen Edgerly, Susan Bakke

المصدر: Clin Cancer Res

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8098eebe68daa7cc4fcbff66216205Test
https://doi.org/10.1158/1078-0432.ccr-08-0938Test

8

Administration of Glucocorticoids to Ovarian Cancer Patients Is Associated with Expression of the Anti-apoptotic Genes SGK1 and MKP1/DUSP1 in Ovarian Tissues

المؤلفون: Suzanne D. Conzen, Amal Melhem, Deanna R. Brickley, S. Diane Yamada, Masha Kocherginsky, Gini F. Fleming, Bertha Delgado, Wei Wu

المصدر: Clinical Cancer Research. 15:3196-3204

مصطلحات موضوعية: Adult, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Blotting, Western, Apoptosis, Ovary, Protein Serine-Threonine Kinases, Biology, Article, Dexamethasone, Immediate early protein, Immediate-Early Proteins, Placebos, Glucocorticoid receptor, Internal medicine, Tumor Cells, Cultured, medicine, Humans, RNA, Messenger, Glucocorticoids, Aged, Aged, 80 and over, Ovarian Neoplasms, Chemotherapy, Reverse Transcriptase Polymerase Chain Reaction, Cancer, Dual Specificity Phosphatase 1, Middle Aged, medicine.disease, Carcinoma, Papillary, Cystadenocarcinoma, Serous, Endocrinology, medicine.anatomical_structure, Oncology, Female, Ovarian cancer, Glucocorticoid, Adenocarcinoma, Clear Cell, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b446d4e708384d6bd1169eeaaadc2d98Test
https://doi.org/10.1158/1078-0432.ccr-08-2131Test

9

Impact of Insulin-Like Growth Factor Type 1 Receptor, Epidermal Growth Factor Receptor, and HER2 Expressions on Outcomes of Patients with Gastric Cancer

المؤلفون: Yoshinori Hirashima, Tetsuya Hamaguchi, Junichi Matsubara, Kuniaki Shirao, Ken Kato, Tadakazu Shimoda, Daisuke Takahari, Yasuhide Yamada, Natsuko Okita, Yasuhiro Shimada

المصدر: Clinical Cancer Research. 14:3022-3029

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32cddc5b7b9a97ea73dd54cbbcb1c3fTest
https://doi.org/10.1158/1078-0432.ccr-07-1898Test

10

Neoadjuvant Treatment of Colorectal Cancer with Bevacizumab: The Perioperative Angiogenic Balance Is Sensitive to Systemic Thrombospondin-1 Levels

المؤلفون: Halina Zommer, Thomas Gruenberger, Christine Brostjan, Harald Freudenthaler, Kristina Gebhardt, Verena Steinrueck, S. Roka, Birgit Gruenberger

المصدر: Clinical Cancer Research. 14:2065-2074

مصطلحات موضوعية: Adult, Male, Vascular Endothelial Growth Factor A, Oncology, Cancer Research, medicine.medical_specialty, Pathology, Bevacizumab, Colorectal cancer, Angiogenesis, medicine.medical_treatment, Neovascularization, Physiologic, Angiogenesis Inhibitors, Antibodies, Monoclonal, Humanized, Thrombospondin 1, chemistry.chemical_compound, Cell Movement, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Neoadjuvant therapy, Aged, Cell Proliferation, Aged, 80 and over, Thymidine Phosphorylase, Wound Healing, Chemotherapy, business.industry, Antibodies, Monoclonal, Endothelial Cells, Combination chemotherapy, Middle Aged, medicine.disease, Neoadjuvant Therapy, Vascular endothelial growth factor, chemistry, Female, Colorectal Neoplasms, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edff4f21b6a283707463777d19ff51e0Test
https://doi.org/10.1158/1078-0432.ccr-07-4081Test

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