نتائج البحث

1

Efficacy of Decitabine plus Anti-PD-1 Camrelizumab in Patients with Hodgkin Lymphoma Who Progressed or Relapsed after PD-1 Blockade Monotherapy

المؤلفون: Miao Liu, Malcolm V. Brock, Qingming Yang, Fengxia Shi, Jing Nie, Liang Dong, Jiejie Liu, Weidong Han, Qian Mei, Chunmeng Wang, Yang Liu, Xiang Li, Meixia Chen

المصدر: Clinical Cancer Research. 27:2782-2791

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Adolescent, Programmed Cell Death 1 Receptor, Decitabine, Kaplan-Meier Estimate, Antibodies, Monoclonal, Humanized, Gastroenterology, B7-H1 Antigen, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Refractory, Recurrence, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, In patient, Child, Neoplasm Staging, business.industry, Anti pd 1, Middle Aged, Prognosis, Hodgkin Disease, Blockade, Treatment Outcome, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Retreatment, Cohort, Disease Progression, Pd 1 blockade, Hodgkin lymphoma, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e09f7bc2baaa5514edccb162437f68Test
https://doi.org/10.1158/1078-0432.ccr-21-0133Test

2

Potent Activity of an Anti-ICAM1 Antibody–Drug Conjugate against Multiple Myeloma

المؤلفون: Daniel W. Sherbenou, Thomas G. Martin, Olivia Perez De Acha, Byron Hann, Blake T. Aftab, Megan Murnane, Yang Su, Jeffery L. Wolf, Shelby C. Bearrows, Bin Liu, Christopher R. Behrens

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 22
Clin Cancer Res

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Immunoconjugates, medicine.medical_treatment, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Monoclonal, Multiple myeloma, Cancer, Tumor, Antibodies, Monoclonal, Hematology, Middle Aged, Intercellular Adhesion Molecule-1, Flow Cytometry, Antibodies, Anti-Idiotypic, Anti-Idiotypic, medicine.anatomical_structure, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Heterografts, Female, Development of treatments and therapeutic interventions, Multiple Myeloma, Biotechnology, Adult, Antibody-drug conjugate, medicine.drug_class, Oncology and Carcinogenesis, Monoclonal antibody, Article, Antibodies, Cell Line, 03 medical and health sciences, Rare Diseases, Clinical Research, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Oncology & Carcinogenesis, Cell Proliferation, Aged, business.industry, Daratumumab, Immunotherapy, medicine.disease, ADP-ribosyl Cyclase 1, Orphan Drug, 030104 developmental biology, Cancer research, Bone marrow, business, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c90915ca7c606383916fa2bf8e189cbTest
https://doi.org/10.1158/1078-0432.ccr-20-0400Test

3

Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers

المؤلفون: Xin Wei Wang, Ole Larsen, Julia S. Johansen, Colm J O'Rourke, Dan Høgdall, Jesper B. Andersen, Morten Mau-Sørensen, Mogens Karsboel Boisen, Astrid Z. Johansen, Dorte Linnemann, Hien Dang, Douglas V. N. P. Oliveira, Valentina M. Factor, Lars Henrik Jensen, Christian Dehlendorff, Mie Grunnet

المصدر: Høgdall, D, O'Rourke, C J, Dehlendorff, C, Larsen, O F, Jensen, L H, Johansen, A Z, Dang, H, Factor, V M, Grunnet, M, Mau-Sørensen, M, Oliveira, D V N P, Linnemann, D, Boisen, M K, Wang, X W, Johansen, J S & Andersen, J B 2020, ' Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers ', Clinical Cancer Research, vol. 26, no. 21, pp. 5655-5667 . https://doi.org/10.1158/1078-0432.CCR-19-2700Test
Clin Cancer Res

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Locally advanced, Inflammation, Deoxycytidine, Article, Disease-Free Survival, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Animals, Humans, Antigens, Tumor-Associated, Carbohydrate, Prognostic biomarker, Chitinase-3-Like Protein 1, Aged, Cell Proliferation, Aged, 80 and over, Interleukin-6, Proportional hazards model, business.industry, Palliative Care, Middle Aged, Prognosis, Receptors, Interleukin-6, Gemcitabine, Progression-Free Survival, Clinical trial, Biliary Tract Neoplasms, 030104 developmental biology, Biliary tract, 030220 oncology & carcinogenesis, Female, medicine.symptom, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1883a3389ee7e27bcc0a6669a1e847Test
https://doi.org/10.1158/1078-0432.ccr-19-2700Test

4

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Paclitaxel, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Triple Negative Breast Neoplasms, Disease, CD8-Positive T-Lymphocytes, Article, B7-H1 Antigen, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Breast cancer, Albumins, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Tumor Microenvironment, medicine, Humans, Aged, Chemotherapy, business.industry, Immunotherapy, Middle Aged, Gene signature, Prognosis, medicine.disease, Neoadjuvant Therapy, Progression-Free Survival, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030104 developmental biology, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Cytokine secretion, Neoplasm Recurrence, Local, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb791e74b1e7256046bab4264aacd2Test
https://doi.org/10.1158/1078-0432.ccr-19-3685Test

5

Angiogenic and Immune-Related Biomarkers and Outcomes Following Axitinib/Pembrolizumab Treatment in Patients with Advanced Renal Cell Carcinoma

المؤلفون: Bradley Rosbrook, Ulka N. Vaishampayan, Toni K. Choueiri, Saby George, David F. McDermott, Daniel C. Cho, Elizabeth R. Plimack, Igor Puzanov, Mayer Fishman, Jean-Francois Martini, Michael B. Atkins, Jamal Tarazi, Kathrine C. Fernandez

المصدر: Clinical Cancer Research. 26:5598-5608

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Axitinib, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Pembrolizumab, Antibodies, Monoclonal, Humanized, Granzymes, Interferon-gamma, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lipocalin-2, Antigens, Neoplasm, Renal cell carcinoma, Internal medicine, Biomarkers, Tumor, medicine, Humans, In patient, 030212 general & internal medicine, Receptors, Immunologic, Carbonic Anhydrase IX, Carcinoma, Renal Cell, Aged, Neoplasm Staging, Whole blood, Dose-Response Relationship, Drug, Neovascularization, Pathologic, business.industry, Exploratory analysis, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Progression-Free Survival, Treatment Outcome, 030220 oncology & carcinogenesis, DEAD Box Protein 58, Female, business, CD8, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d6a37a4ca7925b11f53a9cc5ae1021Test
https://doi.org/10.1158/1078-0432.ccr-20-1408Test

6

PD-L1 Protein Expression on Both Tumor Cells and Macrophages are Associated with Response to Neoadjuvant Durvalumab with Chemotherapy in Triple-negative Breast Cancer

المؤلفون: Kim Blenman, Fahad Shabbir Ahmed, Patricia Gaule, John J. McGuire, David L. Rimm, Lajos Pusztai, Katir K Patel

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, 0301 basic medicine, Cancer Research, Durvalumab, Stromal cell, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Antigens, Differentiation, Myelomonocytic, Triple Negative Breast Neoplasms, B7-H1 Antigen, Article, 03 medical and health sciences, Cytokeratin, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Breast cancer, Immune system, Stroma, Antigens, CD, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Triple-negative breast cancer, Aged, Cell Proliferation, business.industry, Macrophages, Antibodies, Monoclonal, Immunotherapy, Middle Aged, medicine.disease, Neoadjuvant Therapy, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333ffa2e1b4380d458c294bb606f3a2bTest
https://doi.org/10.1158/1078-0432.ccr-20-1303Test

7

Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study

المؤلفون: Burak Gumuscu, Kevin J. Harrington, Hoi-Shen Radcliffe, Lillian L. Siu, Wendy Snyder, Danny Rischin, Beatriz Castelo Fernandez, Ezra E.W. Cohen, Jason Chesney, Anthony Kong, Jonathan D. Cheng, Nicolas Mach

المصدر: Clinical Cancer Research, Vol. 26, No 19 (2020) pp. 5153-5161

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, medicine.medical_treatment, Herpesvirus 1, Human, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Multicenter trial, medicine, Clinical endpoint, Humans, 030212 general & internal medicine, Neoplasm Metastasis, Adverse effect, Aged, ddc:616, Oncolytic Virotherapy, Biological Products, Chemotherapy, Squamous Cell Carcinoma of Head and Neck, business.industry, Middle Aged, medicine.disease, Combined Modality Therapy, Head and neck squamous-cell carcinoma, Progression-Free Survival, 030220 oncology & carcinogenesis, Female, Immunotherapy, Neoplasm Recurrence, Local, Talimogene laherparepvec, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e68d707fa9e943a6b37439bfbf54a5aTest
https://doi.org/10.1158/1078-0432.ccr-20-1170Test

8

Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer

المصدر: Clin Cancer Res

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, In situ hybridization, Nephrectomy, Article, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Tumor-Associated Macrophages, Von Hippel–Lindau tumor suppressor, Basic Helix-Loop-Helix Transcription Factors, Biomarkers, Tumor, medicine, Humans, Genes, Tumor Suppressor, RNA-Seq, Carcinoma, Renal Cell, Aged, Neoplasm Staging, Retrospective Studies, Aged, 80 and over, biology, business.industry, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, Prognosis, medicine.disease, Survival Analysis, Kidney Neoplasms, Gene Expression Regulation, Neoplastic, Clear cell renal cell carcinoma, 030104 developmental biology, MRNA Sequencing, Oncology, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Disease Progression, biology.protein, Cancer research, Immunohistochemistry, Female, Neoplasm Grading, Single-Cell Analysis, business, Kidney cancer, CD163

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80af84e280d3540222d6d04705d792c6Test
https://doi.org/10.1158/1078-0432.ccr-19-3890Test

9

Immunotherapy of Ipilimumab and Nivolumab in Patients with Advanced Neuroendocrine Tumors: A Subgroup Analysis of the CA209-538 Clinical Trial for Rare Cancers

المؤلفون: Ben Markman, Jonathan Cebon, Damien Kee, Michael Michael, Oliver Klein, Clare L. Scott, Craig Underhill, Adnan Nagrial, Louise Jackett, Jodie Palmer, Jane Yeojeong So, Matteo S. Carlino, Caroline Lum, Andreas Behren

المصدر: Clinical Cancer Research. 26:4454-4459

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Ipilimumab, Neuroendocrine tumors, Gastroenterology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Pancreatic cancer, Antineoplastic Combined Chemotherapy Protocols, medicine, Clinical endpoint, Humans, CTLA-4 Antigen, Prospective Studies, 030212 general & internal medicine, Response Evaluation Criteria in Solid Tumors, Aged, Neoplasm Staging, Aged, 80 and over, Everolimus, business.industry, Middle Aged, medicine.disease, Progression-Free Survival, Clinical trial, Neuroendocrine Tumors, Nivolumab, Clinical research, Oncology, 030220 oncology & carcinogenesis, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfb0576b28617790aa7e0eb446129d7Test
https://doi.org/10.1158/1078-0432.ccr-20-0621Test

10

A Serum Protein Classifier Identifying Patients with Advanced Non–Small Cell Lung Cancer Who Derive Clinical Benefit from Treatment with Immune Checkpoint Inhibitors

المؤلفون: Joanna Roder, Carlos R. Oliveira, Egbert F. Smit, Mirte Muller, Heinrich Roder, Kim Monkhorst, Anna-Larissa N. Niemeijer, Joachim G.J.V. Aerts, Karlijn Hummelink, Daan P. Hurkmans

المساهمون: Internal medicine, Pulmonary medicine, AII - Cancer immunology, CCA - Cancer biology and immunology, Pulmonary Medicine

المصدر: Clinical Cancer Research, 26(19), 5188-5197. American Association for Cancer Research Inc.
Clinical Cancer Research, 26(19), 5188-5197. AMER ASSOC CANCER RESEARCH
Muller, M, Hummelink, K, Hurkmans, D P, Niemeijer, A-L N, Monkhorst, K, Roder, J, Oliveira, C, Roder, H, Aerts, J G & Smit, E F 2020, ' A Serum Protein Classifier Identifying Patients with Advanced Non–Small Cell Lung Cancer Who Derive Clinical Benefit from Treatment with Immune Checkpoint Inhibitors ', Clinical Cancer Research, vol. 26, no. 19, pp. 5188-5197 . https://doi.org/10.1158/1078-0432.CCR-20-0538Test

مصطلحات موضوعية: Adult, Male, Proteomics, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Immune checkpoint inhibitors, Programmed Cell Death 1 Receptor, B7-H1 Antigen, Machine Learning, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Text mining, SDG 3 - Good Health and Well-being, Carcinoma, Non-Small-Cell Lung, Internal medicine, Biomarkers, Tumor, medicine, Humans, Prospective Studies, Lung cancer, Prospective cohort study, Immune Checkpoint Inhibitors, Aged, Aged, 80 and over, business.industry, Retrospective cohort study, Blood Proteins, Middle Aged, medicine.disease, Progression-Free Survival, Confidence interval, Gene Expression Regulation, Neoplastic, Treatment Outcome, 030104 developmental biology, Docetaxel, 030220 oncology & carcinogenesis, Female, Nivolumab, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8377fee405dbff046795189b52eb775dTest
https://doi.org/10.1158/1078-0432.ccr-20-0538Test

تنقيح النتائج