From Tumor Immunosuppression to Eradication: Targeting Homing and Activity of Immune Effector Cells to Tumors
| العنوان: | From Tumor Immunosuppression to Eradication: Targeting Homing and Activity of Immune Effector Cells to Tumors |
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| المؤلفون: | Toos Daemen, Oana Draghiciu, Hans W. Nijman |
| المصدر: | Clinical and Developmental Immunology, Vol 2011 (2011) Clinical and Developmental Immunology |
| بيانات النشر: | Hindawi Limited, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | lcsh:Immunologic diseases. Allergy, IMMUNOLOGICAL SELF-TOLERANCE, medicine.medical_treatment, Immunology, SEMLIKI-FOREST-VIRUS, Review Article, Biology, DENDRITIC CELLS, Immune tolerance, Prostate cancer, Immune system, Neoplasms, ANTITUMOR IMMUNITY, Immune Tolerance, medicine, Homeostasis, Humans, Immunology and Allergy, REGULATORY T-CELLS, Indoleamine 2,3-dioxygenase, Immunologic Surveillance, INDOLEAMINE 2, Immunosuppression Therapy, Tumor microenvironment, 3-DIOXYGENASE, BREAST-CANCER CELLS, Immunosuppression, General Medicine, Immunotherapy, medicine.disease, PROSTATE-CANCER, MYELOID SUPPRESSOR-CELLS, lcsh:RC581-607, ENDOTHELIN-B RECEPTOR, Homing (hematopoietic) |
| الوصف: | Unraveling the mechanisms used by the immune system to fight cancer development is one of the most ambitious undertakings in immunology. Detailed knowledge regarding the mechanisms of induction of tolerance and immunosuppression within the tumor microenvironment will contribute to the development of highly effective tumor eradication strategies. Research within the last few decades has shed more light on the matter. This paper aims to give an overview on the current knowledge of the main tolerance and immunosuppression mechanisms elicited within the tumor microenvironment, with the focus on development of effective immunotherapeutic strategies to improve homing and activity of immune effector cells to tumors. |
| تدمد: | 1740-2530 1740-2522 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da405d4fae2a47dc4850672325126907Test https://doi.org/10.1155/2011/439053Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....da405d4fae2a47dc4850672325126907 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17402530 17402522 |
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