دورية أكاديمية
Circulating microRNA Analysis in a Prospective Co-clinical Trial Identifies MIR652-3p as a Response Biomarker and Driver of Regorafenib Resistance Mechanisms in Colorectal Cancer.
| العنوان: | Circulating microRNA Analysis in a Prospective Co-clinical Trial Identifies MIR652-3p as a Response Biomarker and Driver of Regorafenib Resistance Mechanisms in Colorectal Cancer. |
|---|---|
| المؤلفون: | Hedayat, Somaieh, Cascione, Luciano, Cunningham, David, Schirripa, Marta, Lampis, Andrea, Hahne, Jens C, Tunariu, Nina, Hong, Sung Pil, Marchetti, Silvia, Khan, Khurum, Fontana, Elisa, Angerilli, Valentina, Delrieux, Mia, Nava Rodrigues, Daniel, Procaccio, Letizia, Rao, Sheela, Watkins, David, Starling, Naureen, Chau, Ian, Braconi, Chiara, Fotiadis, Nicos, Begum, Ruwaida, Guppy, Naomy, Howell, Louise, Valenti, Melanie, Cribbes, Scott, Kolozsvari, Bernadett, Kirkin, Vladimir, Lonardi, Sara, Ghidini, Michele, Passalacqua, Rodolfo, Elghadi, Raghad, Magnani, Luca, Pinato, David J, Di Maggio, Federica, Ghelardi, Filippo, Sottotetti, Elisa, Vetere, Guglielmo, Ciracì, Paolo, Vlachogiannis, Georgios, Pietrantonio, Filippo, Cremolini, Chiara, Cortellini, Alessio, Loupakis, Fotios, Fassan, Matteo, Valeri, Nicola |
| المصدر: | Clin Cancer Res ; ISSN:1557-3265 ; Volume:30 ; Issue:10 |
| بيانات النشر: | Silverchair Information Systems |
| سنة النشر: | 2024 |
| المجموعة: | PubMed Central (PMC) |
| الوصف: | The multi-kinase inhibitor (mKi) regorafenib has demonstrated efficacy in chemorefractory patients with metastatic colorectal cancer (mCRC). However, lack of predictive biomarkers and concerns over significant toxicities hamper the use of regorafenib in clinical practice. |
| نوع الوثيقة: | article in journal/newspaper report |
| اللغة: | English |
| العلاقة: | https://doi.org/10.1158/1078-0432.CCR-23-2748Test; https://pubmed.ncbi.nlm.nih.gov/38376926Test |
| DOI: | 10.1158/1078-0432.CCR-23-2748 |
| الإتاحة: | https://doi.org/10.1158/1078-0432.CCR-23-2748Test https://pubmed.ncbi.nlm.nih.gov/38376926Test |
| حقوق: | ©2024 American Association for Cancer Research. |
| رقم الانضمام: | edsbas.392A29DA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1158/1078-0432.CCR-23-2748 |
|---|