Gut microbiota analysis and its significance in vasovagal syncope in children
| العنوان: | Gut microbiota analysis and its significance in vasovagal syncope in children |
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| المؤلفون: | Wei Bai, Selena Chen, Chao-Shu Tang, Jian-Guang Qi, Qing-Hua Cui, Ming Xu, Jun-Bao Du, Hong-Fang Jin, Qiang Shi |
| المصدر: | Chinese Medical Journal Chinese Medical Journal, Vol 132, Iss 4, Pp 411-419 (2019) |
| بيانات النشر: | Wolters Kluwer Health, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Ruminococcaceae, Adolescent, lcsh:Medicine, Hemodynamics, Gut microbiota, Gut flora, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Vasovagal syncope, Internal medicine, Ruminococcus, Syncope, Vasovagal, Medicine, Humans, Clinical significance, Child, Children, Feces, biology, business.industry, lcsh:R, General Medicine, Original Articles, biology.organism_classification, medicine.disease, Fatty Acids, Volatile, Gastrointestinal Microbiome, Blood pressure, 030220 oncology & carcinogenesis, Child, Preschool, Mann–Whitney U test, Female, business, 030217 neurology & neurosurgery |
| الوصف: | Background:. Vasovagal syncope (VVS) is common in children and greatly affect both physical and mental health. But the mechanisms have not been completely explained. This study was designed to analyze the gut microbiota in children with VVS and explore its clinical significance. Methods:. Fecal samples from 20 VVS children and 20 matched controls were collected, and the microbiota were analyzed by 16S rRNA gene sequencing. The diversity and microbiota compositions of the VVS cases and controls were compared with the independent sample t test or Mann-Whitney U test. The correlation between the predominant bacteria and clinical symptoms was analyzed using Pearson or Spearman correlation test. Results:. No significant differences in diversity were evident between VVS and controls (P > 0.05). At the family level, the relative abundance of Ruminococcaceae was significantly higher in VVS children than in controls (median [Q1, Q3]: 22.10% [16.89%, 27.36%] vs. 13.92% [10.31%, 20.18%], Z = −2.40, P 4, P |
| اللغة: | English |
| تدمد: | 2542-5641 0366-6999 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64438880ea5481f922d3613e1b8b45ebTest http://europepmc.org/articles/PMC6595724Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....64438880ea5481f922d3613e1b8b45eb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25425641 03666999 |
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