Prediction of massive transfusion in trauma patients in the surgical intensive care units (THAI-SICU study)
| العنوان: | Prediction of massive transfusion in trauma patients in the surgical intensive care units (THAI-SICU study) |
|---|---|
| المؤلفون: | Waraporn Chau-In, Petch Wacharasint, Kaweesak Chittawatanarat, Thammasak Thawitsri, Osaree Akaraborworn, Sujaree Poopipatpab, Sunisa Chatmongkolchart, Chanatthee Kitsiripant, Onuma Chaiwat, Sunthiti Morakul, Chaiyapruk Kusumaphanyo |
| المصدر: | Chinese Journal of Traumatology Chinese Journal of Traumatology, Vol 22, Iss 4, Pp 219-222 (2019) |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Blood transfusion, Critical Care, medicine.medical_treatment, Blood Loss, Surgical, 03 medical and health sciences, 0302 clinical medicine, Intensive care, Coagulopathy, Medicine, Humans, Orthopedics and Sports Medicine, Blood Transfusion, Prospective Studies, Prospective cohort study, Massive bleeding, Aged, 030222 orthopedics, lcsh:R5-920, Sicus, Intraoperative Care, biology, business.industry, Massive transfusion, 030208 emergency & critical care medicine, Multiple trauma, Middle Aged, medicine.disease, biology.organism_classification, Thailand, Surgical intensive care, Confidence interval, Intensive Care Units, Damage control surgery, Emergency medicine, Wounds and Injuries, Surgery, Female, Original Article, business, Packed red blood cells, lcsh:Medicine (General), Forecasting |
| الوصف: | Purpose: After damage control surgery, trauma patients are transferred to intensive care units to restore the physiology. During this period, massive transfusion might be required for ongoing bleeding and coagulopathy. This research aimed to identify predictors of massive blood transfusion in the surgical intensive care units (SICUs). Methods: This is an analysis of the THAI-SICU study which was a prospective cohort that was done in the 9-university-based SICUs in Thailand. The study included only patients admitted due to trauma mechanisms. Massive transfusion was defined as received ≥10 units of packed red blood cells on the first day of admission. Patient characteristics and physiologic data were analyzed to identify the potential factors. A multivariable regression was then performed to identify the significant model. Results: Three hundred and seventy patients were enrolled. Sixteen patients (5%) received massive transfusion in the SICUs. The factors that significantly predicted massive transfusion were an initial sequential organ failure assessment (SOFA) ≥9 (risk difference (RD) 0.13, 95% confidence interval (CI): 0.03- 0.22, p = 0.01); intra-operative blood loss ≥ 4900 mL (RD 0.33, 95% CI: 0.04- 0.62, p = 0.02) and intra-operative blood transfusion ≥ 10 units (RD 0.45, 95% CI: 0.06 to 0.84, p = 0.02). The probability to have massive transfusion was 0.976 in patients who had these 3 factors. Conclusion: Massive blood transfusion in the SICUs occurred in 5%. An initial SOFA ≥9, intra-operative blood loss ≥4900 mL, and intra-operative blood transfusion ≥10 units were the significant factors to predict massive transfusion in the SICUs. Key words: Massive transfusion; Massive bleeding; Surgical intensive care; Multiple trauma |
| تدمد: | 1008-1275 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dcdc6e82afef123340463276e97742Test https://pubmed.ncbi.nlm.nih.gov/31235288Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....03dcdc6e82afef123340463276e97742 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10081275 |
|---|