دورية أكاديمية
Expression and clinical significance of MTA1 in non-small cell lung cancer
| العنوان: | Expression and clinical significance of MTA1 in non-small cell lung cancer |
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| المؤلفون: | Dingbiao LI, Jinxian QIAN, Zhipeng HONG |
| المصدر: | Chinese Journal of Lung Cancer, Vol 11, Iss 6, Pp 775-779 (2008) |
| بيانات النشر: | Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | MTA1 gene, Lung neoplasms, Neoplasm metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Background and objective Metastasis-associated gene 1 (MTA1 ) has been studied deeply recently as a tumor infiltration and metastasis gene. It was expressed in many tumor cell line and was correlated withtumor infiltration and metastasis. The aim of this study is to investigate the relationship between the expression of MTA1and invasion and metastasis of non-small cell lung cancer (NSCLC). Methods Optimal conditions of nested reverse transcription polymerase chain reaction (RT-PCR) were found out; then the expression of MTA1 mRNA in 42 samples of primary carcinoma tissues, paracancerous tissues, normal tissues and corresponding lymph nodes were compared with 20 lung innocence tissues at semi-quantitative level and the results were compared with clinical pathologic data. ResultsAverage expression of the MTA1 gene in NSCLC primary carcinoma tissue (1.50±0.26) and lymph nodes with metastasis (1.88±0.35) was remarkably higher than that in normal tissue (1.02±0.17) and lung innocence tissue (0.90±0.15) (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Chinese |
| تدمد: | 1009-3419 1999-6187 |
| العلاقة: | http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2008.06.04&path%5B%5D=177Test; https://doaj.org/toc/1009-3419Test; https://doaj.org/toc/1999-6187Test |
| الوصول الحر: | https://doaj.org/article/a219e1d3ce71414da6faf6191b7aa364Test |
| رقم الانضمام: | edsdoj.219e1d3ce71414da6faf6191b7aa364 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 10093419 19996187 |
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