التفاصيل البيبلوغرافية
| العنوان: |
A nine-month-old boy with regression of milestones and severe constipation: an unusual case of a large spinal NTRK1 fusion pilocytic astrocytoma. |
| المؤلفون: |
Offenbacher, Rachel, Kobets, Andrew, Dalvi, Nagma, Hsu, Kevin, Chin, Steven, Snuderl, Matija, Levy, Adam, Martin, Allison |
| المصدر: |
Child's Nervous System; Mar2023, Vol. 39 Issue 3, p801-805, 5p |
| مصطلحات موضوعية: |
ASTROCYTOMAS, SPINAL fusion, BRAIN tumors, TUMORS in children, CONSTIPATION, SPINAL cord |
| الشركة/الكيان: |
WORLD Health Organization |
| مستخلص: |
Introduction: Pilocytic astrocytoma, a World Health Organization grade 1 tumor, is the most common brain tumor in children between 5 and 14 years of age and the second most common in children younger than 5 and older than 14. Although classical to the cerebellum and hypothalamic regions, it can also arise in the spinal cord. Larotrectinib, a selective inhibitor of tropomyosin receptor kinase, has been effective in pediatric tumors with NTRK fusion mutations in children as young as 1-month-old. Case: We share the case of a 9-month-old boy who presented with a 4-month history of regression of his milestones and severe constipation who was found to have a large spinal pilocytic astrocytoma with multiple intracranial periventricular lesions. [ABSTRACT FROM AUTHOR] |
|
Copyright of Child's Nervous System is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
