التفاصيل البيبلوغرافية
| العنوان: |
Increased adverse events after percutaneous coronary intervention in patients with COPD: insights from the National Heart, Lung, and Blood Institute dynamic registry. |
| المؤلفون: |
Enriquez JR, Parikh SV, Selzer F, Jacobs AK, Marroquin O, Mulukutla S, Srinivas V, Holper EM, Enriquez, Jonathan R, Parikh, Shailja V, Selzer, Faith, Jacobs, Alice K, Marroquin, Oscar, Mulukutla, Suresh, Srinivas, Vankeepuram, Holper, Elizabeth M |
| المصدر: |
CHEST; Sep2011, Vol. 140 Issue 3, p604-610, 7p |
| مصطلحات موضوعية: |
CORONARY heart disease treatment, CORONARY disease, OBSTRUCTIVE lung diseases, MULTIVARIATE analysis, MYOCARDIAL infarction, MYOCARDIAL revascularization, HEALTH outcome assessment, REOPERATION, RESEARCH funding, TRANSLUMINAL angioplasty, COMORBIDITY, ACQUISITION of data, HOSPITAL mortality, STROKE volume (Cardiac output), CORONARY angiography |
| مصطلحات جغرافية: |
UNITED States |
| الشركة/الكيان: |
NATIONAL Institutes of Health (U.S.) |
| مستخلص: |
Background: Previous studies have demonstrated that patients with COPD are at higher risk for death after percutaneous coronary intervention (PCI), but other clinical outcomes and possible associations with adverse events have not been described.Methods: Using waves 1 through 5 (1999-2006) of the National Heart, Lung, and Blood Institute Dynamic Registry, patients with COPD (n = 860) and without COPD (n = 10,048) were compared. Baseline demographics, angiographic characteristics, and in-hospital and 1-year adverse events were compared.Results: Patients with COPD were older (mean age 66.8 vs 63.2 years, P < .001), more likely to be women, and more likely to have a history of diabetes, prior myocardial infarction, peripheral arterial disease, renal disease, and smoking. Patients with COPD also had a lower mean ejection fraction (49.1% vs 53.0%, P < .001) and a greater mean number of significant lesions (3.2 vs 3.0, P = .006). Rates of in-hospital death (2.2% vs 1.1%, P = .003) and major entry site complications (6.6% vs 4.2%, P < .001) were higher in pulmonary patients. At discharge, pulmonary patients were significantly less likely to be prescribed aspirin (92.4% vs 95.3%, P < .001), β-blockers (55.7% vs 76.2%, P < .001), and statins (60.0% vs 66.8%, P < .001). After adjustment, patients with COPD had significantly increased risk of death (hazard ratio [HR] = 1.30, 95% CI = 1.01-1.67) and repeat revascularization (HR = 1.22, 95% CI = 1.02-1.46) at 1 year, compared with patients without COPD.Conclusions: COPD is associated with higher mortality rates and repeat revascularization within 1 year after PCI. These higher rates of adverse outcomes may be associated with lower rates of guideline-recommended class 1 medications prescribed at discharge. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
