A gold-nanodot-decorated hollow carbon nanosphere based nanoplatform for intracellular miRNA imaging in colorectal cancer cells
| العنوان: | A gold-nanodot-decorated hollow carbon nanosphere based nanoplatform for intracellular miRNA imaging in colorectal cancer cells |
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| المؤلفون: | Zheng Wang, Jinglei Xu, Huiling Fan, Jiangbo Xi, Guobin Wang, Shijun Lei, Heng Xiao, Lin Wang, Zhiyin Pei, Luming Xu |
| المصدر: | Chemical Communications. 55:12352-12355 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Carbon nanosphere, Surface Properties, Colorectal cancer, Metal Nanoparticles, chemistry.chemical_element, 010402 general chemistry, Endocytosis, 01 natural sciences, Catalysis, microRNA, Materials Chemistry, medicine, Hyaluronic Acid, Particle Size, biology, 010405 organic chemistry, Chemistry, Optical Imaging, CD44, Metals and Alloys, General Chemistry, medicine.disease, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, MicroRNAs, Hyaluronan Receptors, Ceramics and Composites, biology.protein, Biophysics, Gold, Nanodot, Colorectal Neoplasms, Porosity, Carbon, Intracellular |
| الوصف: | We report a new biofunctionalized nanoplatform based on hyaluronic acid-coated gold-nano-dot-decorated hollow carbon nanospheres (AuHCNs-HA) for microRNA imaging in living cells. Importantly, the HA-coated nanoplatform could be internalized into target cells via CD44 receptor-mediated endocytosis. It can be further applied for intracellular miR-21 imaging in CD44-positive colorectal cancer cells. |
| تدمد: | 1364-548X 1359-7345 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f53e9eebef44cadaa8410f3d4ca6dbTest https://doi.org/10.1039/c9cc06674hTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....e7f53e9eebef44cadaa8410f3d4ca6db |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
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