نتائج البحث - "Glucagon-Like Peptide-1 Receptor"

المساهمون: Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), Université de Lille, Détection, évaluation, gestion des risques CHROniques et éMErgents (CHROME) / Université de Nîmes (CHROME), Université de Nîmes (UNIMES), Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), ANR-17-CE14-0034,BETAPLASTICITY,Identification du rôle du facteur de transcription E2F1 dans l'identité et la plasticité de la cellule bétâ pancréatique(2017), ANR-16-IDEX-0004,ULNE,ULNE(2016)

المصدر: Cell Reports
Cell Reports, 2022, 40 (6), pp.111170. ⟨10.1016/j.celrep.2022.111170⟩

مصطلحات موضوعية: Glucose, Diabetes Mellitus, Type 2, [SDV]Life Sciences [q-bio], Insulin-Secreting Cells, Exenatide, Humans, Insulin, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, General Biochemistry, Genetics and Molecular Biology, E2F1 Transcription Factor, Glucagon-Like Peptide-1 Receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8059f1ee5af23e05214ce25a0741573Test
https://pubmed.ncbi.nlm.nih.gov/35947949Test

4

Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes

المؤلفون: Xin Zhang, Patrick M. Sexton, Yi Lynn Liang, Denise Wootten, Radostin Danev, Matthew J. Belousoff

المصدر: Cell Reports, Vol 36, Iss 2, Pp 109374-(2021)

مصطلحات موضوعية: Models, Molecular, endocrine system, QH301-705.5, media_common.quotation_subject, cryoelectron microscopy, Glucagon-Like Peptides, Taspoglutide, Peptide, Type 2 diabetes, Carbohydrate metabolism, Pharmacology, General Biochemistry, Genetics and Molecular Biology, GPCRs, Glucagon-Like Peptide-1 Receptor, Cell Line, Structure-Activity Relationship, Protein Domains, GTP-Binding Proteins, medicine, Humans, Biology (General), Receptor, G protein-coupled receptor, media_common, GLP-1R, chemistry.chemical_classification, semaglutide, Chemistry, Semaglutide, digestive, oral, and skin physiology, Appetite, medicine.disease, Multiprotein Complexes, Peptides, GPCR dynamics, hormones, hormone substitutes, and hormone antagonists, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24add099cb0536b8b9a8494936633129Test
https://pubmed.ncbi.nlm.nih.gov/34260945Test

5

GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension

المؤلفون: Samyuktha Guttha, Ahmara G. Ross, Albert Bargoud, Joshua L. Dunaief, Katherine E. Uyhazi, Qi N. Cui, Jacob Sterling, Modupe O Adetunji

المصدر: Cell reports
Cell Reports, Vol 33, Iss 5, Pp 108271-(2020)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, Retinal Ganglion Cells, medicine.drug_class, A1 reactive astrocyte, Retinal ganglion, General Biochemistry, Genetics and Molecular Biology, Glucagon-Like Peptide-1 Receptor, Article, neuroinflammation, 03 medical and health sciences, 0302 clinical medicine, Interleukin-1alpha, medicine, Animals, retinal ganglion cell, lcsh:QH301-705.5, Neuroinflammation, Intraocular Pressure, Inflammation, CD11b Antigen, Microglia, Cell Death, business.industry, Tumor Necrosis Factor-alpha, Complement C1q, Neurodegeneration, medicine.disease, NLY01, Astrogliosis, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, glaucoma, Retinal ganglion cell, lcsh:Biology (General), Astrocytes, Cancer research, Female, Ocular Hypertension, sense organs, Neuron death, business, 030217 neurology & neurosurgery, Retinal Neurons

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefbbe4473e0fef67bbd9ae0a48e5acaTest
https://pubmed.ncbi.nlm.nih.gov/33147455Test

6

β Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice

المؤلفون: Kyle W. Sloop, M. Dodson Michael, Leanne R. Donahue, Karolina E. Zaborska, Darline Garibay, Andrew C. White, Jon Lou, Bethany P. Cummings, Margot H. Weissman, Andrew D. Miller, Seon A. Lee, Erica A. Sloma

المصدر: Cell Reports, Vol 23, Iss 4, Pp 967-973 (2018)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Cell, Prohormone convertase, Bariatric Surgery, Proglucagon, General Biochemistry, Genetics and Molecular Biology, Article, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Paracrine signalling, Mice, Gastrectomy, Insulin-Secreting Cells, Paracrine Communication, medicine, Animals, Secretion, Receptor, lcsh:QH301-705.5, Mice, Knockout, geography, geography.geographical_feature_category, Chemistry, digestive, oral, and skin physiology, Islet, Cell biology, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), Glucagon-Secreting Cells, Knockout mouse, Proprotein Convertases, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e471a5e60fdd1f288c92ccdce3048e8Test
http://www.sciencedirect.com/science/article/pii/S2211124718304960Test

7

The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

المؤلفون: Christina N. Heiss, Randy J. Seeley, Ying Shiuan Lee, Fredrik Bäckhed, Anna Håkansson Gladh, Daniel J. Drucker, Louise Mannerås-Holm, Julia Serrano-Lobo, Louise E. Olofsson

المصدر: Heiss, C N, Mannerås-Holm, L, Lee, Y S, Serrano-Lobo, J, Håkansson Gladh, A, Seeley, R J, Drucker, D J, Bäckhed, F & Olofsson, L E 2021, ' The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism ', Cell Reports, vol. 35, no. 8, 109163 . https://doi.org/10.1016/j.celrep.2021.109163Test

مصطلحات موضوعية: Leptin, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, diet-induced obesity, Hypothalamus, microglia, Gut flora, Glucagon-Like Peptide-1 Receptor, General Biochemistry, Genetics and Molecular Biology, leptin sensitivity, Mice, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Animals, Humans, Obesity, Receptor, hypothalamic inflammation, Inflammation, gut microbiota, Glial fibrillary acidic protein, biology, Microglia, digestive, oral, and skin physiology, astrocytes, biology.organism_classification, medicine.disease, Glucagon-like peptide-1, Gastrointestinal Microbiome, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, glucagon-like peptide-1, Diet, Western, biology.protein, medicine.symptom, GLP-1, Weight gain, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1246c48efc4ba88cddca0f7c9a69b5f7Test
https://doi.org/10.1016/j.celrep.2021.109163Test

8

Glucagon-like Peptide 1 Receptor Signaling in Acinar Cells Causes Growth-Dependent Release of Pancreatic Enzymes

المؤلفون: Carolyn F. Deacon, Reidar Albrechtsen, Rune E. Kuhre, Lasse Bremholm, Charlotte Janus, Elisa P. Jensen, Nicolai J. Wewer Albrechtsen, Linda Hilsted, Steen Seier Poulsen, Berit Svendsen, C. Christiansen, Jens J. Holst, Bolette Hartmann

المصدر: Albrechtsen, N J W, Albrechtsen, R, Bremholm, L, Svendsen, B, Kuhre, R E, Poulsen, S S, Christiansen, C B, Jensen, E P, Janus, C, Hilsted, L, Deacon, C F, Hartmann, B & Holst, J J 2016, ' Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes ', Cell Reports, vol. 17, no. 11, pp. 2845-2856 . https://doi.org/10.1016/j.celrep.2016.11.051Test

مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_specialty, Incretin, 030209 endocrinology & metabolism, Acinar Cells, Incretins, Gene Expression Regulation, Enzymologic, Glucagon-Like Peptide-1 Receptor, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Internal medicine, medicine, Animals, Humans, Amylase, Epidermal growth factor receptor, Receptor, Pancreas, Cell Proliferation, biology, Forkhead Box Protein O1, digestive, oral, and skin physiology, Lipase, medicine.disease, Glucagon-like peptide-1, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Pancreatitis, Amylases, Pancreatic juice, biology.protein, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43e7682a70527e6c33c012213932100Test
https://doi.org/10.1016/j.celrep.2016.11.051Test

9

Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action

المؤلفون: Erin E. Mulvihill, Laurie L. Baggio, Daniel J. Drucker, Elodie M. Varin, Jacqueline A. Koehler, Randy J. Seeley, Xiemin Cao

المصدر: Cell Reports, Vol 27, Iss 11, Pp 3371-3384.e3 (2019)

مصطلحات موضوعية: 0301 basic medicine, Nervous system, Male, medicine.medical_specialty, Recombinant Fusion Proteins, Glucagon-Like Peptides, Incretin, Wnt1 Protein, Biology, Incretins, General Biochemistry, Genetics and Molecular Biology, Energy homeostasis, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Eating, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1, Internal medicine, medicine, Glucose homeostasis, Animals, Homeostasis, Receptor, lcsh:QH301-705.5, 2. Zero hunger, Homeodomain Proteins, Neurons, Gastric emptying, digestive, oral, and skin physiology, Brain, Glucagon-like peptide-1, Immunoglobulin Fc Fragments, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Glucose, lcsh:Biology (General), Gastric Emptying, Enteric nervous system, 030217 neurology & neurosurgery, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08b49278dc05d955ee4b254135fe406Test
https://pubmed.ncbi.nlm.nih.gov/31189118Test

تنقيح النتائج