المؤلفون: Varca, Anthony C.^1,2 (AUTHOR), Casalena, Dominick³ (AUTHOR), Chan, Wai Cheung^1,2,4,5 (AUTHOR), Hu, Bin^1,2 (AUTHOR), Magin, Robert S.^1,2 (AUTHOR), Roberts, Rebekka M.^1,2 (AUTHOR), Liu, Xiaoxi^1,2 (AUTHOR), Zhu, He^1,4,5,6 (AUTHOR), Seo, Hyuk-Soo¹ (AUTHOR), Dhe-Paganon, Sirano¹ (AUTHOR), Marto, Jarrod A.^1,4,5 (AUTHOR), Auld, Douglas³ (AUTHOR), Buhrlage, Sara J.^1,2 (AUTHOR) saraj_buhrlage@dfci.harvard.edu

المصدر: Cell Chemical Biology. Dec2021, Vol. 28 Issue 12, p1758-1758. 1p.

مصطلحات موضوعية: *HIGH throughput screening (Drug development), *DEUBIQUITINATING enzymes, *DRUG target, *UBIQUITIN, *ENZYME inhibitors

المؤلفون: Harvey, Edward P.^1,2 (AUTHOR), Hauseman, Zachary J.^1,2 (AUTHOR), Cohen, Daniel T.^1,2 (AUTHOR), Rettenmaier, T. Justin³ (AUTHOR), Lee, Susan^1,2 (AUTHOR), Huhn, Annissa J.^1,2 (AUTHOR), Wales, Thomas E.⁴ (AUTHOR), Seo, Hyuk-Soo⁵ (AUTHOR), Luccarelli, James^1,2 (AUTHOR), Newman, Catherine E.^1,2 (AUTHOR), Guerra, Rachel M.^1,2 (AUTHOR), Bird, Gregory H.^1,2 (AUTHOR), Dhe-Paganon, Sirano⁵ (AUTHOR), Engen, John R.⁴ (AUTHOR), Wells, James A.³ (AUTHOR), Walensky, Loren D.^1,2 (AUTHOR) loren_walensky@dfci.harvard.edu

المصدر: Cell Chemical Biology. Jun2020, Vol. 27 Issue 6, p647-647. 1p.

مصطلحات موضوعية: *ONCOGENIC proteins, *SMALL molecules, *CONFORMATIONAL analysis, *APOPTOSIS, *BCL-2 proteins, *DISULFIDES

المؤلفون: Sivakumaren, Sindhu Carmen^1,2 (AUTHOR), Shim, Hyeseok^1,3 (AUTHOR), Zhang, Tinghu^1,2 (AUTHOR), Ferguson, Fleur M.^1,2 (AUTHOR), Lundquist, Mark R.³ (AUTHOR), Browne, Christopher M.^1,2 (AUTHOR), Seo, Hyuk-Soo^1,2 (AUTHOR), Paddock, Marcia N.³ (AUTHOR), Manz, Theresa D.^1,2,4 (AUTHOR), Jiang, Baishan^1,2 (AUTHOR), Hao, Ming-Feng^1,2 (AUTHOR), Krishnan, Pranav⁵ (AUTHOR), Wang, Diana G.³ (AUTHOR), Yang, T. Jonathan³ (AUTHOR), Kwiatkowski, Nicholas P.^1,2,6 (AUTHOR), Ficarro, Scott B.^1,7,8 (AUTHOR), Cunningham, James M.⁵ (AUTHOR), Marto, Jarrod A.^1,7,8,9 (AUTHOR), Dhe-Paganon, Sirano^1,2 (AUTHOR), Cantley, Lewis C.^1,3 (AUTHOR) lcantley@med.cornell.edu

المصدر: Cell Chemical Biology. May2020, Vol. 27 Issue 5, p525-525. 1p.

مصطلحات موضوعية: *CANCER cell proliferation, *DELETION mutation, *SMALL molecules, *LIPIDS, *CELL lines

المؤلفون: Lamberto, Ilaria¹, Liu, Xiaoxi¹, Seo, Hyuk-Soo¹, Schauer, Nathan J.¹, Iacob, Roxana E.², Hu, Wanyi¹, Das, Deepika³, Mikhailova, Tatiana⁴, Weisberg, Ellen L.³, Engen, John R.², Anderson, Kenneth C.³, Chauhan, Dharminder³, Dhe-Paganon, Sirano¹ dhepag@crystal.harvard.edu, Buhrlage, Sara J.^1,4 saraj_buhrlage@dfci.harvard.edu

المصدر: Cell Chemical Biology. Dec2017, Vol. 24 Issue 12, p1490-1500.e11. 1p.

مصطلحات موضوعية: *BINDING sites, *PROTEOLYSIS, *UBIQUITINATION, *ONCOGENES, *SMALL molecules