التفاصيل البيبلوغرافية
العنوان:
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
المؤلفون:
Matthew Gagne , Juan I. Moliva , Kathryn E. Foulds , Shayne F. Andrew , Barbara J. Flynn , Anne P. Werner , Danielle A. Wagner , I-Ting Teng , Bob C. Lin , Christopher Moore , Nazaire Jean-Baptiste , Robin Carroll , Stephanie L. Foster , Mit Patel , Madison Ellis , Venkata-Viswanadh Edara , Nahara Vargas Maldonado , Mahnaz Minai , Lauren McCormick , Christopher Cole Honeycutt , Bianca M. Nagata , Kevin W. Bock , Caitlyn N.M. Dulan , Jamilet Cordon , Dillon R. Flebbe , John-Paul M. Todd , Elizabeth McCarthy , Laurent Pessaint , Alex Van Ry , Brandon Narvaez , Daniel Valentin , Anthony Cook , Alan Dodson , Katelyn Steingrebe , Saule T. Nurmukhambetova , Sucheta Godbole , Amy R. Henry , Farida Laboune , Jesmine Roberts-Torres , Cynthia G. Lorang , Shivani Amin , Jessica Trost , Mursal Naisan , Manjula Basappa , Jacquelyn Willis , Lingshu Wang , Wei Shi , Nicole A. Doria-Rose , Yi Zhang , Eun Sung Yang , Kwanyee Leung , Sijy O’Dell , Stephen D. Schmidt , Adam S. Olia , Cuiping Liu , Darcy R. Harris , Gwo-Yu Chuang , Guillaume Stewart-Jones , Isabella Renzi , Yen-Ting Lai , Agata Malinowski , Kai Wu , John R. Mascola , Andrea Carfi , Peter D. Kwong , Darin K. Edwards , Mark G. Lewis , Hanne Andersen , Kizzmekia S. Corbett , Martha C. Nason , Adrian B. McDermott , Mehul S. Suthar , Ian N. Moore , Mario Roederer , Nancy J. Sullivan , Daniel C. Douek , Robert A. Seder
المصدر:
Cell . 185:1556-1571.e18
بيانات النشر:
Elsevier BV, 2022.
سنة النشر:
2022
مصطلحات موضوعية:
SARS-CoV-2 , Animals , COVID-19 , Macaca , RNA, Messenger , Antibodies, Viral , Antibodies, Neutralizing , General Biochemistry, Genetics and Molecular Biology , 2019-nCoV Vaccine mRNA-1273
الوصف:
SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to neutralization following immunization with ancestral spike-matched vaccines. It is unclear whether boosting with Omicron-matched vaccines would enhance protection. Here, nonhuman primates that received mRNA-1273 at weeks 0 and 4 were boosted at week 41 with mRNA-1273 or mRNA-Omicron. Neutralizing titers against D614G were 4,760 and 270 reciprocal ID
تدمد:
0092-8674
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b66941abd2f84105e968afdfeb4097Test https://doi.org/10.1016/j.cell.2022.03.038Test
حقوق:
CLOSED
رقم الانضمام:
edsair.doi.dedup.....b4b66941abd2f84105e968afdfeb4097
قاعدة البيانات:
OpenAIRE
