دورية أكاديمية

Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma: A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma.

التفاصيل البيبلوغرافية
العنوان: Rhabdomyosarcoma with Pseudolipoblasts Arising in Ovarian Carcinosarcoma: A Distinctive Postchemotherapy Morphologic Variant Mimicking Pleomorphic Liposarcoma.
المؤلفون: Thway, Khin, Hazell, Steve, Banerjee, Susana, Fisher, Cyril
المصدر: Case Reports in Radiology; 2014, p1-5, 5p
مصطلحات موضوعية: RHABDOMYOSARCOMA, LIPOSARCOMA, SARCOMA, CANCER chemotherapy, MORPHOLOGY
مستخلص: We describe a case of ovarian carcinosarcoma occurring in a 60-year-old female. The neoplasm was excised after neoadjuvant chemotherapy and contained a predominant heterologous pleomorphic rhabdomyosarcomatous component in which there were numerous multivacuolated rhabdomyoblasts that strongly mimicked lipoblasts. The clear cell variant of rhabdomyosarcomais rarely documented, but this case shows a highly unusual finding in which the rhabdomyoblasts show the prominent multivacuolation with nuclear indentation characteristic of and indistinguishable from pleomorphic lipoblasts. This appears to represent a posttreatment phenomenon. As this finding might conceivably occur in other rhabdomyosarcomas after chemotherapy, we highlight the potential for diagnostic confusion with pleomorphic liposarcoma, which is usually diagnosed bymorphology so that immunohistochemistry for muscle markers might not be performed. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:20906862
DOI:10.1155/2014/238545