دورية أكاديمية
أعرض في EDS

Pediatric Collagenous Gastroenterocolitis Successfully Treated with Methotrexate

التفاصيل البيبلوغرافية
العنوان: Pediatric Collagenous Gastroenterocolitis Successfully Treated with Methotrexate
المؤلفون: Beate C. Beinvogl, Jeffrey D. Goldsmith, Ramalingam Arumugam, Michelle Kennedy, Mani Mokalla, Paul A. Rufo, Menno Verhave
المصدر: Case Reports in Pediatrics, Vol 2020 (2020)
بيانات النشر: Hindawi Limited, 2020.
سنة النشر: 2020
المجموعة: LCC:Pediatrics
مصطلحات موضوعية: Pediatrics, RJ1-570
الوصف: A two-and-one-half-year-old previously healthy female presented with a ten-week history of watery diarrhea, nonbilious and nonbloody emesis, and low-grade fevers. She was found to have severe hypoalbuminemia and hypogammaglobulinemia. Her symptoms persisted, and she became dependent on parenteral nutrition. Biopsies obtained during subsequent endoscopic and colonoscopic studies revealed findings consistent with collagenous gastroenterocolitis. She responded to an empiric course of prednisone, but her symptoms recurred shortly after transitioning to oral budesonide. After successful reinduction with intravenous prednisone, intramuscular methotrexate was initiated. She remained asymptomatic during a 15-month course of therapy, and she continued to do well clinically until approximately nine months after weaning off methotrexate. At that point, she experienced a recurrence of diarrhea, and repeat endoscopic evaluation confirmed collagenous colitis. This responded nicely to a short course of oral budesonide, and she has since remained asymptomatic and off any therapy.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2090-6803
2090-6811
العلاقة: https://doaj.org/toc/2090-6803Test; https://doaj.org/toc/2090-6811Test
DOI: 10.1155/2020/1929581
الوصول الحر: https://doaj.org/article/e124f5ad690940b39757aa4ff787650eTest
رقم الانضمام: edsdoj.124f5ad690940b39757aa4ff787650e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20906803
20906811
DOI:10.1155/2020/1929581