Marine-Lenhart Syndrome: Case Report, Diagnosis, and Management
| العنوان: | Marine-Lenhart Syndrome: Case Report, Diagnosis, and Management |
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| المؤلفون: | Francesco Vendrame, Danielle Rachel Neuman, Russ Kuker |
| المصدر: | Case Reports in Endocrinology, Vol 2018 (2018) Case Reports in Endocrinology |
| بيانات النشر: | Hindawi Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | medicine.medical_specialty, endocrine system, Exophthalmos, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Eye disease, medicine.medical_treatment, 030209 endocrinology & metabolism, Case Report, Disease, Hot Nodule, lcsh:Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, Methimazole, 0302 clinical medicine, medicine, Thyroid uptake, lcsh:RC648-665, business.industry, Thyroid, Thyroidectomy, medicine.disease, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Radiology, medicine.symptom, business, medicine.drug |
| الوصف: | The coexistence of thyroid functioning nodules and Graves’ disease is called Marine-Lenhart syndrome. This condition is estimated to occur in 0.8-2.7% of patients with Graves’ disease with few cases reported in the literature. Criteria for the diagnosis are not well defined. Here, we present a case of hyperthyroidism characterized by the presence of stimulating TSH receptor antibodies and severe bilateral exophthalmos. A thyroid uptake and scan revealed an elevated 24-hour iodine-131 uptake and a discrete hot nodule in the upper pole of the right lobe which was also observed with a thyroid ultrasound. The patient was diagnosed with Marine-Lenhart syndrome complicated by thyroid eye disease and was treated with methimazole followed by thyroidectomy and orbital decompression. We review the existing literature and propose criteria for the diagnosis and treatment of this condition. |
| اللغة: | English |
| تدمد: | 2090-6501 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76dd4fc1943d342ad02418b7d6025581Test https://doaj.org/article/c44e399dfc1841fe8a903626c491dd25Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....76dd4fc1943d342ad02418b7d6025581 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20906501 |
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