A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment
| العنوان: | A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment |
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| المؤلفون: | Ju Young Kim, Hyun Jung Kim |
| المصدر: | Case Reports in Cardiology, Vol 2014 (2014) Case Reports in Cardiology |
| بيانات النشر: | Hindawi Limited, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Coronary artery aneurysm, medicine.medical_specialty, Pediatrics, lcsh:Diseases of the circulatory (Cardiovascular) system, business.industry, Incidence (epidemiology), Case Report, medicine.disease, Infliximab, Surgery, medicine.anatomical_structure, Aneurysm, Refractory, lcsh:RC666-701, Internal medicine, hemic and lymphatic diseases, medicine, Cardiology, Methotrexate, Kawasaki disease, Cardiology and Cardiovascular Medicine, business, medicine.drug, Artery |
| الوصف: | Kawasaki disease is an acute febrile illness that usually occurs in children younger than 5 years of age. The use of intravenous immunoglobulin (IVIG) within the first 10 days of illness has been shown to reduce the incidence of coronary artery aneurysms significantly. The relative roles of repeated doses of intravenous immunoglobulin (IVIG) are controversial in refractory Kawasaki disease (KD). Most experts recommend the second retreatment with IVIG, 2 g/kg in refractory KD. However, the dose-response effect of the third or fourth IVIG was uncertain. Although there have been a significant number of reports on new therapeutic options for refractory KD, such as steroid, infliximab, methotrexate, and other immunosuppressants, their effectiveness in reducing the prevalence of coronary artery aneurysms was unproven. We present here KD patient with small coronary artery aneurysm who is resistant to the third IVIG and steroid pulse therapy but showed improvement immediately after the infusion of the 4th IVIG on fever day 18. |
| اللغة: | English |
| تدمد: | 2090-6412 2090-6404 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a87b0c9ac907d4a8bba4edf015a74cTest https://doaj.org/article/abc84702d16d4e989e1b9c8a8d2a0e87Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....69a87b0c9ac907d4a8bba4edf015a74c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20906412 20906404 |
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